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Chemically modified in-vitro-transcribed mRNA encoding thrombopoietin stimulates thrombopoiesis in mice

The use of messenger RNA (mRNA) enables the transient production of therapeutic proteins with stable and predictable translational kinetics and without the risk of insertional mutagenesis. Recent findings highlight the enormous potential of mRNA-based therapeutics. Here, we describe the synthesis of...

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Detalles Bibliográficos
Autores principales:	Zhang, Yu, Xi, Xiaodong, Yu, Hang, Yang, Liuyan, Lin, Jinzhong, Yang, Wen, Liu, Junling, Fan, Xuemei, Xu, Yingjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440273/ https://www.ncbi.nlm.nih.gov/pubmed/36090760 http://dx.doi.org/10.1016/j.omtn.2022.08.017

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