Cargando…
STAT6 in mitochondrial outer membrane impairs mitochondrial fusion by inhibiting MFN2 dimerization
Although it is reported that mitochondria-localized nuclear transcription factors (TFs) regulate mitochondrial processes such as apoptosis and mitochondrial transcription/respiration, the functions and mechanisms of mitochondrial dynamics regulated by mitochondria-localized nuclear TFs are yet to be...
Autores principales: | Kim, Hyunmi, Park, Soo Jung, Jou, Ilo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440285/ https://www.ncbi.nlm.nih.gov/pubmed/36065189 http://dx.doi.org/10.1016/j.isci.2022.104923 |
Ejemplares similares
-
Mfn1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion
por: Cao, Yu-Lu, et al.
Publicado: (2017) -
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
por: Chen, Hsiuchen, et al.
Publicado: (2003) -
Epigenetic downregulation of STAT6 increases HIF-1α expression via mTOR/S6K/S6, leading to enhanced hypoxic viability of glioma cells
por: Park, Soo Jung, et al.
Publicado: (2019) -
FUNDC2 promotes liver tumorigenesis by inhibiting MFN1-mediated mitochondrial fusion
por: Li, Shuaifeng, et al.
Publicado: (2022) -
The Role of Impaired Mitochondrial Dynamics in MFN2-Mediated Pathology
por: Zaman, Mashiat, et al.
Publicado: (2022)