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Quantitative modeling of human liver reveals dysregulation of glycosphingolipid pathways in nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is an increasingly prevalent disease that is associated with multiple metabolic disturbances, yet the metabolic pathways underlying its progression are poorly understood. Here, we studied metabolic pathways of the human liver across the full histological spec...

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Detalles Bibliográficos
Autores principales: Sen, Partho, Govaere, Olivier, Sinioja, Tim, McGlinchey, Aidan, Geng, Dawei, Ratziu, Vlad, Bugianesi, Elisabetta, Schattenberg, Jörn M., Vidal-Puig, Antonio, Allison, Michael, Cockell, Simon, Daly, Ann K., Hyötyläinen, Tuulia, Anstee, Quentin M., Orešič, Matej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440293/
https://www.ncbi.nlm.nih.gov/pubmed/36065182
http://dx.doi.org/10.1016/j.isci.2022.104949