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Quantitative modeling of human liver reveals dysregulation of glycosphingolipid pathways in nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is an increasingly prevalent disease that is associated with multiple metabolic disturbances, yet the metabolic pathways underlying its progression are poorly understood. Here, we studied metabolic pathways of the human liver across the full histological spec...
Autores principales: | Sen, Partho, Govaere, Olivier, Sinioja, Tim, McGlinchey, Aidan, Geng, Dawei, Ratziu, Vlad, Bugianesi, Elisabetta, Schattenberg, Jörn M., Vidal-Puig, Antonio, Allison, Michael, Cockell, Simon, Daly, Ann K., Hyötyläinen, Tuulia, Anstee, Quentin M., Orešič, Matej |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440293/ https://www.ncbi.nlm.nih.gov/pubmed/36065182 http://dx.doi.org/10.1016/j.isci.2022.104949 |
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