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Enteroendocrine cell expression of split-GAL4 drivers bearing regulatory sequences associated with panneuronally expressed genes in Drosophila melanogaster
In Drosophila melanogaster , hormone-secreting enteroendocrine cells are important for communication from the midgut to other tissues. Many lexA, GAL4, and split-GAL4 drivers that direct gene expression in enteroendocrine cells also confer expression in hormone-secreting cells of the central nervous...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Caltech Library
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440388/ https://www.ncbi.nlm.nih.gov/pubmed/36065255 http://dx.doi.org/10.17912/micropub.biology.000628 |
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author | Holsopple, Jessica M. Cook, Kevin R. Popodi, Ellen M. |
author_facet | Holsopple, Jessica M. Cook, Kevin R. Popodi, Ellen M. |
author_sort | Holsopple, Jessica M. |
collection | PubMed |
description | In Drosophila melanogaster , hormone-secreting enteroendocrine cells are important for communication from the midgut to other tissues. Many lexA, GAL4, and split-GAL4 drivers that direct gene expression in enteroendocrine cells also confer expression in hormone-secreting cells of the central nervous system. This study examines the midgut expression of selected lexA, GAL4, and split-GAL4 transgenes carrying enhancer fragments previously associated with panneuronal gene expression to assess the experimental usefulness of these drivers for distinguishing the endocrine influences of CNS versus midgut cells on physiological processes. |
format | Online Article Text |
id | pubmed-9440388 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Caltech Library |
record_format | MEDLINE/PubMed |
spelling | pubmed-94403882022-09-04 Enteroendocrine cell expression of split-GAL4 drivers bearing regulatory sequences associated with panneuronally expressed genes in Drosophila melanogaster Holsopple, Jessica M. Cook, Kevin R. Popodi, Ellen M. MicroPubl Biol Materials and Reagents In Drosophila melanogaster , hormone-secreting enteroendocrine cells are important for communication from the midgut to other tissues. Many lexA, GAL4, and split-GAL4 drivers that direct gene expression in enteroendocrine cells also confer expression in hormone-secreting cells of the central nervous system. This study examines the midgut expression of selected lexA, GAL4, and split-GAL4 transgenes carrying enhancer fragments previously associated with panneuronal gene expression to assess the experimental usefulness of these drivers for distinguishing the endocrine influences of CNS versus midgut cells on physiological processes. Caltech Library 2022-08-19 /pmc/articles/PMC9440388/ /pubmed/36065255 http://dx.doi.org/10.17912/micropub.biology.000628 Text en Copyright: © 2022 by the authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Materials and Reagents Holsopple, Jessica M. Cook, Kevin R. Popodi, Ellen M. Enteroendocrine cell expression of split-GAL4 drivers bearing regulatory sequences associated with panneuronally expressed genes in Drosophila melanogaster |
title |
Enteroendocrine cell expression of split-GAL4 drivers bearing regulatory sequences associated with panneuronally expressed genes in
Drosophila melanogaster
|
title_full |
Enteroendocrine cell expression of split-GAL4 drivers bearing regulatory sequences associated with panneuronally expressed genes in
Drosophila melanogaster
|
title_fullStr |
Enteroendocrine cell expression of split-GAL4 drivers bearing regulatory sequences associated with panneuronally expressed genes in
Drosophila melanogaster
|
title_full_unstemmed |
Enteroendocrine cell expression of split-GAL4 drivers bearing regulatory sequences associated with panneuronally expressed genes in
Drosophila melanogaster
|
title_short |
Enteroendocrine cell expression of split-GAL4 drivers bearing regulatory sequences associated with panneuronally expressed genes in
Drosophila melanogaster
|
title_sort | enteroendocrine cell expression of split-gal4 drivers bearing regulatory sequences associated with panneuronally expressed genes in
drosophila melanogaster |
topic | Materials and Reagents |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440388/ https://www.ncbi.nlm.nih.gov/pubmed/36065255 http://dx.doi.org/10.17912/micropub.biology.000628 |
work_keys_str_mv | AT holsopplejessicam enteroendocrinecellexpressionofsplitgal4driversbearingregulatorysequencesassociatedwithpanneuronallyexpressedgenesindrosophilamelanogaster AT cookkevinr enteroendocrinecellexpressionofsplitgal4driversbearingregulatorysequencesassociatedwithpanneuronallyexpressedgenesindrosophilamelanogaster AT popodiellenm enteroendocrinecellexpressionofsplitgal4driversbearingregulatorysequencesassociatedwithpanneuronallyexpressedgenesindrosophilamelanogaster |