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Rejuvenated endothelial progenitor cells through overexpression of cellular prion protein effectively salvaged the critical limb ischemia in rats with preexisting chronic kidney disease

BACKGROUND: This study tested the hypothesis that overexpression of cellular prion protein in endothelial progenitor cells (PrPc(OE)-EPCs), defined as “rejuvenated EPCs,” was superior to EPCs for salvaging the critical limb ischemia (CLI) induced after 28-day chronic kidney disease (CKD) induction i...

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Detalles Bibliográficos
Autores principales:	Yeh, Jui-Po, Sung, Pei‐Hsun, Chiang, John Y., Huang, Chi-Ruei, Chen, Yi-Ling, Lai, Jui-Pin, Sheu, Jiunn-Jye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440498/ https://www.ncbi.nlm.nih.gov/pubmed/36056416 http://dx.doi.org/10.1186/s13287-022-03119-0

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