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Pyrazinamide Resistance and pncA Mutation Profiles in Multidrug Resistant Mycobacterium Tuberculosis

PURPOSE: Pyrazinamide (PZA) is a critical component of standardized chemotherapy for tuberculosis (TB) and is recommended for the treatment of multidrug-resistant (MDR) TB. We aimed to characterize mutations in pncA of M. tuberculosis and evaluate their diagnostic accuracy for PZA susceptibility in...

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Detalles Bibliográficos
Autores principales: Shi, Dawei, Zhou, Qiulong, Xu, Sihong, Zhu, Yumei, Li, Hui, Xu, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440668/
https://www.ncbi.nlm.nih.gov/pubmed/36065280
http://dx.doi.org/10.2147/IDR.S368444

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