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Lumican is elevated in the lung in human and experimental acute respiratory distress syndrome and promotes early fibrotic responses to lung injury

BACKGROUND: Fibroproliferative repair starts early in the inflammatory phase of acute respiratory distress syndrome (ARDS) and indicates a poor prognosis. Lumican, a small leucine-rich proteoglycan, is implicated in homeostasis and fibrogenesis, but its role in ARDS is unclear. METHODS: Bronchoalveo...

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Detalles Bibliográficos
Autores principales:	Wang, Ke, Wang, Youyu, Cao, Yufang, Wang, Hao, Zhou, Yongfang, Gao, Lijuan, Zeng, Zijian, Cheng, Mengxin, Jin, Xiaodong, Chen, Jun, Wen, Fuqiang, Wang, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440861/ https://www.ncbi.nlm.nih.gov/pubmed/36059026 http://dx.doi.org/10.1186/s12967-022-03597-z

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