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Controllable synthesis of conjugated microporous polymer films for ultrasensitive detection of chemical warfare agents

Nerve agents, one of the most toxic chemical warfare agents, seriously threaten human life and public security. The high toxicity of nerve agents makes the development of fluorescence sensors with suitable limit of detection challenging. Here, we propose a sensor design based on a conjugated micropo...

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Autores principales: Mo, Wanqi, Zhu, Zihao, Kong, Fanwei, Li, Xiaobai, Chen, Yu, Liu, Huaqian, Cheng, Zhiyong, Ma, Hongwei, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440894/
https://www.ncbi.nlm.nih.gov/pubmed/36057648
http://dx.doi.org/10.1038/s41467-022-32878-w
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author Mo, Wanqi
Zhu, Zihao
Kong, Fanwei
Li, Xiaobai
Chen, Yu
Liu, Huaqian
Cheng, Zhiyong
Ma, Hongwei
Li, Bin
author_facet Mo, Wanqi
Zhu, Zihao
Kong, Fanwei
Li, Xiaobai
Chen, Yu
Liu, Huaqian
Cheng, Zhiyong
Ma, Hongwei
Li, Bin
author_sort Mo, Wanqi
collection PubMed
description Nerve agents, one of the most toxic chemical warfare agents, seriously threaten human life and public security. The high toxicity of nerve agents makes the development of fluorescence sensors with suitable limit of detection challenging. Here, we propose a sensor design based on a conjugated microporous polymer film for the detection of diethyl chlorophosphate, a substitute of Sarin, with low detection limit of 2.5 ppt. This is due to the synergy of the susceptible on-off effect of hybridization and de-hybridization of hybrid local and charge transfer (HLCT) materials and the microporous structure of CMP films facilitating the inward diffusion of DCP vapors, and the extended π-conjugated structure. This strategy provides a new idea for the future development of gas sensors. In addition, a portable sensor is successfully integrated based on TCzP-CMP films that enables wireless, remote, ultrasensitive, and real-time detection of DCP vapors.
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spelling pubmed-94408942022-09-05 Controllable synthesis of conjugated microporous polymer films for ultrasensitive detection of chemical warfare agents Mo, Wanqi Zhu, Zihao Kong, Fanwei Li, Xiaobai Chen, Yu Liu, Huaqian Cheng, Zhiyong Ma, Hongwei Li, Bin Nat Commun Article Nerve agents, one of the most toxic chemical warfare agents, seriously threaten human life and public security. The high toxicity of nerve agents makes the development of fluorescence sensors with suitable limit of detection challenging. Here, we propose a sensor design based on a conjugated microporous polymer film for the detection of diethyl chlorophosphate, a substitute of Sarin, with low detection limit of 2.5 ppt. This is due to the synergy of the susceptible on-off effect of hybridization and de-hybridization of hybrid local and charge transfer (HLCT) materials and the microporous structure of CMP films facilitating the inward diffusion of DCP vapors, and the extended π-conjugated structure. This strategy provides a new idea for the future development of gas sensors. In addition, a portable sensor is successfully integrated based on TCzP-CMP films that enables wireless, remote, ultrasensitive, and real-time detection of DCP vapors. Nature Publishing Group UK 2022-09-03 /pmc/articles/PMC9440894/ /pubmed/36057648 http://dx.doi.org/10.1038/s41467-022-32878-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Mo, Wanqi
Zhu, Zihao
Kong, Fanwei
Li, Xiaobai
Chen, Yu
Liu, Huaqian
Cheng, Zhiyong
Ma, Hongwei
Li, Bin
Controllable synthesis of conjugated microporous polymer films for ultrasensitive detection of chemical warfare agents
title Controllable synthesis of conjugated microporous polymer films for ultrasensitive detection of chemical warfare agents
title_full Controllable synthesis of conjugated microporous polymer films for ultrasensitive detection of chemical warfare agents
title_fullStr Controllable synthesis of conjugated microporous polymer films for ultrasensitive detection of chemical warfare agents
title_full_unstemmed Controllable synthesis of conjugated microporous polymer films for ultrasensitive detection of chemical warfare agents
title_short Controllable synthesis of conjugated microporous polymer films for ultrasensitive detection of chemical warfare agents
title_sort controllable synthesis of conjugated microporous polymer films for ultrasensitive detection of chemical warfare agents
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440894/
https://www.ncbi.nlm.nih.gov/pubmed/36057648
http://dx.doi.org/10.1038/s41467-022-32878-w
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