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Miniaturized antenna verified with diffuse optical measurements for native and boiled adipose tissue differentiation

Medical industries are continuously working towards the development of wearable theragnostic devices which enable monitoring various ailments in the body and then transmitting them to the base-station. The antenna design is of prime importance where the suitable design guarantees proper communicatio...

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Detalles Bibliográficos
Autores principales: Halim, Ashraf S. Abdel, Mostafa, Mohanad, Hamdy, Omnia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440913/
https://www.ncbi.nlm.nih.gov/pubmed/36057671
http://dx.doi.org/10.1038/s41598-022-19430-y
Descripción
Sumario:Medical industries are continuously working towards the development of wearable theragnostic devices which enable monitoring various ailments in the body and then transmitting them to the base-station. The antenna design is of prime importance where the suitable design guarantees proper communication between the antenna and the base-station. In this paper, a co-planar wave-guide antenna is proposed for the use in the medical implant communication service (MICS) band for data transmission. The proposed antenna is studied for ex-vivo applications where the antenna is simulated for bovine intramuscular fat (adipose tissue). The preliminary results showed that the antenna radiates in MICS band. Two types of samples are tested; namely, native fat and boiled fat. The boiled fat is used in order to represent the infected fat tissue. Hence, the antenna was implanted into the fat samples and the results revealed noticeable variations in the radiation characteristics between native and boiled fat. Different parameters of the proposed antenna including the reflection coefficient (S(11)), radiation patterns, gain, efficiency, and front-to-back ratio are investigated. The simulations showed that S(11) parameter was − 12.4 dB in MICS band for the normal fat. On the other hand, the measured S(11) values were − 12.3 dB for the native samples and − 9.9 dB for the boiled fat samples. To assert the variation in the biological characteristics of the boiled fat as compared to those of the native fat, diffuse optical measurements of the examined samples were investigated. Such variation in the light scattering and absorbance by the tissue is responsible for varying the S(11) parameter for each case. The results have shown that the proposed design is a good candidate for detecting the change in biological tissue.