Identification of risk loci for primary aldosteronism in genome-wide association studies

Primary aldosteronism affects up to 10% of hypertensive patients and is responsible for treatment resistance and increased cardiovascular risk. Here we perform a genome-wide association study in a discovery cohort of 562 cases and 950 controls and identify three main loci on chromosomes 1, 13 and X;...

Descripción completa

Detalles Bibliográficos
Autores principales: Le Floch, Edith, Cosentino, Teresa, Larsen, Casper K., Beuschlein, Felix, Reincke, Martin, Amar, Laurence, Rossi, Gian-Paolo, De Sousa, Kelly, Baron, Stéphanie, Chantalat, Sophie, Saintpierre, Benjamin, Lenzini, Livia, Frouin, Arthur, Giscos-Douriez, Isabelle, Ferey, Matthis, Abdellatif, Alaa B., Meatchi, Tchao, Empana, Jean-Philippe, Jouven, Xavier, Gieger, Christian, Waldenberger, Melanie, Peters, Annette, Cusi, Daniele, Salvi, Erika, Meneton, Pierre, Touvier, Mathilde, Deschasaux, Mélanie, Druesne-Pecollo, Nathalie, Boulkroun, Sheerazed, Fernandes-Rosa, Fabio L., Deleuze, Jean-François, Jeunemaitre, Xavier, Zennaro, Maria-Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440917/
https://www.ncbi.nlm.nih.gov/pubmed/36057693
http://dx.doi.org/10.1038/s41467-022-32896-8

Ejemplares similares

Ejemplares similares