Taz protects hematopoietic stem cells from an aging-dependent decrease in PU.1 activity

Specific functions of the immune system are essential to protect us from infections caused by pathogens such as viruses and bacteria. However, as we age, the immune system shows a functional decline that can be attributed in large part to age-associated defects in hematopoietic stem cells (HSCs)—the...

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Detalles Bibliográficos
Autores principales: Kim, Kyung Mok, Mura-Meszaros, Anna, Tollot, Marie, Krishnan, Murali Shyam, Gründl, Marco, Neubert, Laura, Groth, Marco, Rodriguez-Fraticelli, Alejo, Svendsen, Arthur Flohr, Campaner, Stefano, Andreas, Nico, Kamradt, Thomas, Hoffmann, Steve, Camargo, Fernando D., Heidel, Florian H., Bystrykh, Leonid V., de Haan, Gerald, von Eyss, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440927/
https://www.ncbi.nlm.nih.gov/pubmed/36057685
http://dx.doi.org/10.1038/s41467-022-32970-1

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