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Case reports of management of aplastic anemia after COVID-19 vaccination: a single institute experience in Taiwan

Global vaccination against the coronavirus disease 2019 (COVID-19) is thought to be the most effective way to end or at least contain the COVID-19 pandemic. However, despite the good safety profiles and effectiveness of the available COVID-19 vaccines, rare but serious hematological complications ha...

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Detalles Bibliográficos
Autores principales: Chen, Chia-Yu, Chen, Tzu-Ting, Hsieh, Ching-Yun, Lien, Ming-Yu, Yeh, Su-Peng, Chen, Chi-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440996/
https://www.ncbi.nlm.nih.gov/pubmed/36057889
http://dx.doi.org/10.1007/s12185-022-03445-2
Descripción
Sumario:Global vaccination against the coronavirus disease 2019 (COVID-19) is thought to be the most effective way to end or at least contain the COVID-19 pandemic. However, despite the good safety profiles and effectiveness of the available COVID-19 vaccines, rare but serious hematological complications have emerged, including thromboembolic outcomes with thrombocytopenia following the ChAdOx1 nCoV-19 (Oxford-AstraZeneca) and Ad26.COV.2.S (Johnson & Johnson/Janssen) vaccines. Moreover, COVID-19 vaccination may be linked to the development of aplastic anemia (AA). We discuss four cases of AA that arose after COVID-19 vaccination in our hospital and two other such cases identified in our literature review.