Case reports of management of aplastic anemia after COVID-19 vaccination: a single institute experience in Taiwan

Global vaccination against the coronavirus disease 2019 (COVID-19) is thought to be the most effective way to end or at least contain the COVID-19 pandemic. However, despite the good safety profiles and effectiveness of the available COVID-19 vaccines, rare but serious hematological complications ha...

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Autores principales: Chen, Chia-Yu, Chen, Tzu-Ting, Hsieh, Ching-Yun, Lien, Ming-Yu, Yeh, Su-Peng, Chen, Chi-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440996/
https://www.ncbi.nlm.nih.gov/pubmed/36057889
http://dx.doi.org/10.1007/s12185-022-03445-2
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author Chen, Chia-Yu
Chen, Tzu-Ting
Hsieh, Ching-Yun
Lien, Ming-Yu
Yeh, Su-Peng
Chen, Chi-Ching
author_facet Chen, Chia-Yu
Chen, Tzu-Ting
Hsieh, Ching-Yun
Lien, Ming-Yu
Yeh, Su-Peng
Chen, Chi-Ching
author_sort Chen, Chia-Yu
collection PubMed
description Global vaccination against the coronavirus disease 2019 (COVID-19) is thought to be the most effective way to end or at least contain the COVID-19 pandemic. However, despite the good safety profiles and effectiveness of the available COVID-19 vaccines, rare but serious hematological complications have emerged, including thromboembolic outcomes with thrombocytopenia following the ChAdOx1 nCoV-19 (Oxford-AstraZeneca) and Ad26.COV.2.S (Johnson & Johnson/Janssen) vaccines. Moreover, COVID-19 vaccination may be linked to the development of aplastic anemia (AA). We discuss four cases of AA that arose after COVID-19 vaccination in our hospital and two other such cases identified in our literature review.
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spelling pubmed-94409962022-09-06 Case reports of management of aplastic anemia after COVID-19 vaccination: a single institute experience in Taiwan Chen, Chia-Yu Chen, Tzu-Ting Hsieh, Ching-Yun Lien, Ming-Yu Yeh, Su-Peng Chen, Chi-Ching Int J Hematol Case Report Global vaccination against the coronavirus disease 2019 (COVID-19) is thought to be the most effective way to end or at least contain the COVID-19 pandemic. However, despite the good safety profiles and effectiveness of the available COVID-19 vaccines, rare but serious hematological complications have emerged, including thromboembolic outcomes with thrombocytopenia following the ChAdOx1 nCoV-19 (Oxford-AstraZeneca) and Ad26.COV.2.S (Johnson & Johnson/Janssen) vaccines. Moreover, COVID-19 vaccination may be linked to the development of aplastic anemia (AA). We discuss four cases of AA that arose after COVID-19 vaccination in our hospital and two other such cases identified in our literature review. Springer Nature Singapore 2022-09-04 2023 /pmc/articles/PMC9440996/ /pubmed/36057889 http://dx.doi.org/10.1007/s12185-022-03445-2 Text en © Japanese Society of Hematology 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Case Report
Chen, Chia-Yu
Chen, Tzu-Ting
Hsieh, Ching-Yun
Lien, Ming-Yu
Yeh, Su-Peng
Chen, Chi-Ching
Case reports of management of aplastic anemia after COVID-19 vaccination: a single institute experience in Taiwan
title Case reports of management of aplastic anemia after COVID-19 vaccination: a single institute experience in Taiwan
title_full Case reports of management of aplastic anemia after COVID-19 vaccination: a single institute experience in Taiwan
title_fullStr Case reports of management of aplastic anemia after COVID-19 vaccination: a single institute experience in Taiwan
title_full_unstemmed Case reports of management of aplastic anemia after COVID-19 vaccination: a single institute experience in Taiwan
title_short Case reports of management of aplastic anemia after COVID-19 vaccination: a single institute experience in Taiwan
title_sort case reports of management of aplastic anemia after covid-19 vaccination: a single institute experience in taiwan
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440996/
https://www.ncbi.nlm.nih.gov/pubmed/36057889
http://dx.doi.org/10.1007/s12185-022-03445-2
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