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Inflammatory macrophages interrupt osteocyte maturation and mineralization via regulating the Notch signaling pathway

BACKGROUND: It is well-known that both macrophages and osteocytes are critical regulators of osteogenesis and osteoclastogenesis, yet there is limited understanding of the macrophage-osteocyte interaction, and how their crosstalk could affect bone homeostasis and mineralization. This research theref...

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Detalles Bibliográficos
Autores principales: Wang, Shengfang, Xiao, Lan, Prasadam, Indira, Crawford, Ross, Zhou, Yinghong, Xiao, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441044/
https://www.ncbi.nlm.nih.gov/pubmed/36058911
http://dx.doi.org/10.1186/s10020-022-00530-4

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