Transforming growth factor-β-induced secretion of extracellular vesicles from oral cancer cells evokes endothelial barrier instability via endothelial-mesenchymal transition

BACKGROUND: During metastasis, cancer cells undergo epithelial-mesenchymal transition (EMT) in response to transforming growth factor-β (TGF-β), which is abundant in the tumor microenvironment, and acquire invasive and metastatic potentials. Metastasis to distant organs requires intravascular invasi...

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Detalles Bibliográficos
Autores principales: Kobayashi, Miho, Fujiwara, Kashio, Takahashi, Kazuki, Yoshioka, Yusuke, Ochiya, Takahiro, Podyma-Inoue, Katarzyna A., Watabe, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441046/
https://www.ncbi.nlm.nih.gov/pubmed/36057626
http://dx.doi.org/10.1186/s41232-022-00225-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441046/
https://www.ncbi.nlm.nih.gov/pubmed/36057626
http://dx.doi.org/10.1186/s41232-022-00225-7

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