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Heme oxygenase 1 overexpression induces immune evasion of acute myeloid leukemia against natural killer cells by inhibiting CD48

BACKGROUND: Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. Given the high relapse rate, more effective treatments are needed to improve clinical outcomes. We previously demonstrated that heme oxygenase 1 (HO1) is overexpressed in AML, while the functional roles of...

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Detalles Bibliográficos
Autores principales:	Zhang, Tianzhuo, Fang, Qin, Liu, Ping, Wang, Ping, Feng, Cheng, Wang, Jishi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441067/ https://www.ncbi.nlm.nih.gov/pubmed/36058936 http://dx.doi.org/10.1186/s12967-022-03589-z

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