Cargando…

Protective Effects of Pioglitazone on Cognitive Impairment and the Underlying Mechanisms: A Review of Literature

Pioglitazone, a peroxisome proliferator-activated receptor gamma (PPARγ) agonist, is known to have anti-inflammatory and anti-oxidant effects on the brain, and its clinical potential in the treatment of cognitive impairment in diseases such as Alzheimer's disease (AD) and Parkinson disease (PD)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alhowail, Ahmad, Alsikhan, Rawan, Alsaud, May, Aldubayan, Maha, Rabbani, Syed Imam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441149/ https://www.ncbi.nlm.nih.gov/pubmed/36068789 http://dx.doi.org/10.2147/DDDT.S367229

Ejemplares similares

The Ameliorative Effect of Pioglitazone against Neuroinflammation Caused by Doxorubicin in Rats
por: Alsaud, May M., et al.
Publicado: (2023)

Protective Effect of Galantamine against Doxorubicin-Induced Neurotoxicity
por: Alsikhan, Rawan S., et al.
Publicado: (2023)

Mechanisms Underlying Cognitive Impairment Induced by Prenatal Alcohol Exposure
por: Alhowail, Ahmad
Publicado: (2022)

The Impact of Metformin on the Development of Hypothyroidism and Cardiotoxicity Induced by Cyclophosphamide, Methotrexate, and Fluorouracil in Rats
por: Alhowail, Ahmad H., et al.
Publicado: (2023)

Influence of pioglitazone on experimental heart failure and hyperlipidemia in rats
por: Biswas, Arghya, et al.
Publicado: (2012)

Neuroprotective Effect of Clobenpropit against Lipopolysaccharide-Induced Cognitive Deficits via Attenuating Neuroinflammation and Enhancing Mitochondrial Functions in Mice
por: Mani, Vasudevan, et al.
Publicado: (2021)

Vitamin B17 Ameliorates Methotrexate-Induced Reproductive Toxicity, Oxidative Stress, and Testicular Injury in Male Rats
por: Felemban, Shatha G., et al.
Publicado: (2020)

Sukkari dates seed improves type-2 diabetes mellitus-induced memory impairment by reducing blood glucose levels and enhancing brain cholinergic transmission: In vivo and molecular modeling studies
por: Mani, Vasudevan, et al.
Publicado: (2022)

Factors Affecting the Incidence, Progression, and Severity of COVID-19 in Type 1 Diabetes Mellitus
por: Ahmed, Amira S., et al.
Publicado: (2021)

Evaluation of the Cardiac Protection Conferred by Proanthocyanidins in Grape Seeds against Development of Ehrlich Solid Tumors in Mice
por: Aldubayan, Maha Abdulrahman
Publicado: (2020)

Molecular insights into the benefits of nicotine on memory and cognition
por: Alhowail, Ahmad
Publicado: (2021)

Formulation of Ethyl Cellulose Microparticles Incorporated Pheophytin A Isolated from Suaeda vermiculata for Antioxidant and Cytotoxic Activities
por: Mohammed, Hamdoon A., et al.
Publicado: (2019)

Linking COVID-19 and Parkinson's disease: Targeting the role of Vitamin-D
por: Behl, Tapan, et al.
Publicado: (2021)

Health status outcome among cannabis addicts after treatment of addiction
por: Siwar, Mohammed Ali A. L., et al.
Publicado: (2023)

Research advances on how metformin improves memory impairment in “chemobrain”
por: Alhowail, Ahmad, et al.
Publicado: (2021)

Pioglitazone abolishes cognition impairments as well as BDNF and neurotensin disturbances in a rat model of autism
por: Kirsten, Thiago B., et al.
Publicado: (2019)

Silver Citrate Nanoparticles Inhibit PMA-Induced TNFα Expression via Deactivation of NF-κB Activity in Human Cancer Cell-Lines, MCF-7
por: Abdellatif, Ahmed A H, et al.
Publicado: (2020)

Effects of Pioglitazone or Exercise in Older Adults with Mild Cognitive Impairment and Insulin Resistance: A Pilot Study
por: Hildreth, Kerry L., et al.
Publicado: (2015)

The efficacy of pioglitazone for renal protection in diabetic kidney disease
por: Ho, Chao-Chung, et al.
Publicado: (2022)

Protective role of glibenclamide against nicotinamide-streptozotocin induced nuclear damage in diabetic Wistar rats
por: Rabbani, Syed Imam, et al.
Publicado: (2010)

Physico-Chemical Study of Mn(II), Co(II), Cu(II), Cr(III), and Pd(II) Complexes with Schiff-Base and Aminopyrimidyl Derivatives and Anti-Cancer, Antioxidant, Antimicrobial Applications
por: Al-Fakeh, Maged S., et al.
Publicado: (2023)

Magnesium Increases the Protective Effect of Citicoline on Aluminum Chloride-induced Cognitive Impairment
por: Hosseini-Sharifabad, Ali, et al.
Publicado: (2020)

How Does Pioglitazone Prevent Progression of Impaired Glucose Tolerance to Diabetes?
por: Genuth, Saul M.
Publicado: (2013)

Pioglitazone: Indian perspective
por: Shukla, Rishi, et al.
Publicado: (2011)

Protective effect of pioglitazone on morphine-induced neuroinflammation in the rat lumbar spinal cord
por: Charkhpour, Mohammad, et al.
Publicado: (2015)

Piracetam as a Therapeutic Agent for Doxorubicin-Induced Cognitive Deficits by Enhancing Cholinergic Functions and Reducing Neuronal Inflammation, Apoptosis, and Oxidative Stress in Rats
por: Mani, Vasudevan, et al.
Publicado: (2022)

Pioglitazone-Induced Acute Rhabdomyolysis
por: Slim, Raoudha, et al.
Publicado: (2009)

Investigation of the antibacterial activity of pioglitazone
por: Masadeh, Majed M, et al.
Publicado: (2011)

Usage of pioglitazone at Medanta, the Medicity
por: Mithal, Ambrish, et al.
Publicado: (2014)

Pioglitazone: A prudent prescription
por: Kalra, Sanjay, et al.
Publicado: (2013)

Reassessment of Pioglitazone for Alzheimer’s Disease
por: Saunders, Ann M., et al.
Publicado: (2021)

Therapeutic effect and potential mechanism of pioglitazone in rats with severe acute pancreatitis
por: Hai, Wang, et al.
Publicado: (2017)

Pioglitazone is equally effective for diabetes prevention in older versus younger adults with impaired glucose tolerance
por: Espinoza, Sara E., et al.
Publicado: (2016)

Evaluation of patients’ knowledge about their medications: A cross-sectional study in Qassim region, Saudi Arabia
por: Alfadl, Abubakr Abdelraouf, et al.
Publicado: (2023)

Cognitive Impairment and Brain Reorganization in MS: Underlying Mechanisms and the Role of Neurorehabilitation
por: Nasios, Grigorios, et al.
Publicado: (2020)

Evaluation of Acute Toxicity of Pioglitazone in Mice
por: Chinnam, Pushpalatha, et al.
Publicado: (2012)

Pioglitazone, bladder cancer, and detection bias
por: Dolin, Paul
Publicado: (2014)

Current clinical evidence on pioglitazone pharmacogenomics
por: Kawaguchi-Suzuki, Marina, et al.
Publicado: (2013)

Pioglitazone: A review of analytical methods
por: Satheeshkumar, N., et al.
Publicado: (2014)

Influence of trazodone on the pharmacodynamics and pharmacokinetics of pioglitazone
por: Pradeepkumar, Bhupalam, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_mdc41828sl845rngsr4sda99va