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Severe Intermittent Hypoxia Modulates the Macrophage Phenotype and Impairs Wound Healing Through Downregulation of HIF-2α

BACKGROUND: Obstructive sleep apnea is prevalent in patients with diabetic foot ulcers, while the effect of intermittent hypoxia on wound healing is unclear. The objective of this study was to investigate the effect of severe intermittent hypoxia on wound healing. METHODS: C57BL/6 mice were exposed...

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Detalles Bibliográficos
Autores principales:	Chen, Lihong, Gao, Yunyi, Li, Yan, Wang, Chun, Chen, Dawei, Gao, Yun, Ran, Xingwu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441177/ https://www.ncbi.nlm.nih.gov/pubmed/36068885 http://dx.doi.org/10.2147/NSS.S382275

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