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FAM: focal attention module for lesion segmentation of COVID-19 CT images

The novel coronavirus pneumonia (COVID-19) is the world’s most serious public health crisis, posing a serious threat to public health. In clinical practice, automatic segmentation of the lesion from computed tomography (CT) images using deep learning methods provides an promising tool for identifyin...

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Autores principales: Wu, Xiaoxin, Zhang, Zhihao, Guo, Lingling, Chen, Hui, Luo, Qiaojie, Jin, Bei, Gu, Weiyan, Lu, Fangfang, Chen, Jingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441194/
https://www.ncbi.nlm.nih.gov/pubmed/36091622
http://dx.doi.org/10.1007/s11554-022-01249-5
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author Wu, Xiaoxin
Zhang, Zhihao
Guo, Lingling
Chen, Hui
Luo, Qiaojie
Jin, Bei
Gu, Weiyan
Lu, Fangfang
Chen, Jingjing
author_facet Wu, Xiaoxin
Zhang, Zhihao
Guo, Lingling
Chen, Hui
Luo, Qiaojie
Jin, Bei
Gu, Weiyan
Lu, Fangfang
Chen, Jingjing
author_sort Wu, Xiaoxin
collection PubMed
description The novel coronavirus pneumonia (COVID-19) is the world’s most serious public health crisis, posing a serious threat to public health. In clinical practice, automatic segmentation of the lesion from computed tomography (CT) images using deep learning methods provides an promising tool for identifying and diagnosing COVID-19. To improve the accuracy of image segmentation, an attention mechanism is adopted to highlight important features. However, existing attention methods are of weak performance or negative impact to the accuracy of convolutional neural networks (CNNs) due to various reasons (e.g. low contrast of the boundary between the lesion and the surrounding, the image noise). To address this issue, we propose a novel focal attention module (FAM) for lesion segmentation of CT images. FAM contains a channel attention module and a spatial attention module. In the spatial attention module, it first generates rough spatial attention, a shape prior of the lesion region obtained from the CT image using median filtering and distance transformation. The rough spatial attention is then input into two 7 × 7 convolution layers for correction, achieving refined spatial attention on the lesion region. FAM is individually integrated with six state-of-the-art segmentation networks (e.g. UNet, DeepLabV3+, etc.), and then we validated these six combinations on the public dataset including COVID-19 CT images. The results show that FAM improve the Dice Similarity Coefficient (DSC) of CNNs by 2%, and reduced the number of false negatives (FN) and false positives (FP) up to 17.6%, which are significantly higher than that using other attention modules such as CBAM and SENet. Furthermore, FAM significantly improve the convergence speed of the model training and achieve better real-time performance. The codes are available at GitHub (https://github.com/RobotvisionLab/FAM.git).
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spelling pubmed-94411942022-09-06 FAM: focal attention module for lesion segmentation of COVID-19 CT images Wu, Xiaoxin Zhang, Zhihao Guo, Lingling Chen, Hui Luo, Qiaojie Jin, Bei Gu, Weiyan Lu, Fangfang Chen, Jingjing J Real Time Image Process Original Research Paper The novel coronavirus pneumonia (COVID-19) is the world’s most serious public health crisis, posing a serious threat to public health. In clinical practice, automatic segmentation of the lesion from computed tomography (CT) images using deep learning methods provides an promising tool for identifying and diagnosing COVID-19. To improve the accuracy of image segmentation, an attention mechanism is adopted to highlight important features. However, existing attention methods are of weak performance or negative impact to the accuracy of convolutional neural networks (CNNs) due to various reasons (e.g. low contrast of the boundary between the lesion and the surrounding, the image noise). To address this issue, we propose a novel focal attention module (FAM) for lesion segmentation of CT images. FAM contains a channel attention module and a spatial attention module. In the spatial attention module, it first generates rough spatial attention, a shape prior of the lesion region obtained from the CT image using median filtering and distance transformation. The rough spatial attention is then input into two 7 × 7 convolution layers for correction, achieving refined spatial attention on the lesion region. FAM is individually integrated with six state-of-the-art segmentation networks (e.g. UNet, DeepLabV3+, etc.), and then we validated these six combinations on the public dataset including COVID-19 CT images. The results show that FAM improve the Dice Similarity Coefficient (DSC) of CNNs by 2%, and reduced the number of false negatives (FN) and false positives (FP) up to 17.6%, which are significantly higher than that using other attention modules such as CBAM and SENet. Furthermore, FAM significantly improve the convergence speed of the model training and achieve better real-time performance. The codes are available at GitHub (https://github.com/RobotvisionLab/FAM.git). Springer Berlin Heidelberg 2022-09-04 2022 /pmc/articles/PMC9441194/ /pubmed/36091622 http://dx.doi.org/10.1007/s11554-022-01249-5 Text en © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Research Paper
Wu, Xiaoxin
Zhang, Zhihao
Guo, Lingling
Chen, Hui
Luo, Qiaojie
Jin, Bei
Gu, Weiyan
Lu, Fangfang
Chen, Jingjing
FAM: focal attention module for lesion segmentation of COVID-19 CT images
title FAM: focal attention module for lesion segmentation of COVID-19 CT images
title_full FAM: focal attention module for lesion segmentation of COVID-19 CT images
title_fullStr FAM: focal attention module for lesion segmentation of COVID-19 CT images
title_full_unstemmed FAM: focal attention module for lesion segmentation of COVID-19 CT images
title_short FAM: focal attention module for lesion segmentation of COVID-19 CT images
title_sort fam: focal attention module for lesion segmentation of covid-19 ct images
topic Original Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441194/
https://www.ncbi.nlm.nih.gov/pubmed/36091622
http://dx.doi.org/10.1007/s11554-022-01249-5
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