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Drug Resistance Mutations and Associated Phenotypes Detected in Clinical Trials of Maribavir for Treatment of Cytomegalovirus Infection

BACKGROUND: In separate phase 2 trials, 120 patients received maribavir for cytomegalovirus (CMV) infection failing conventional therapy (trial 202) and 119 received maribavir for asymptomatic infection (trial 203). Overall, 172 cleared their CMV infection (CMV DNA <200 copies/mL) within 6 weeks....

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Detalles Bibliográficos
Autores principales: Chou, Sunwen, Song, Kening, Wu, Jingyang, Bo, Tien, Crumpacker, Clyde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441206/
https://www.ncbi.nlm.nih.gov/pubmed/32726419
http://dx.doi.org/10.1093/infdis/jiaa462