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HIV-1 infection enhances innate function and TLR7 expression in female plasmacytoid dendritic cells

Plasmacytoid dendritic cells (pDCs) express TLR7, a ssRNA-sensor encoded on the X chromosome, which escapes X chromosome inactivation (XCI) in females. pDCs are specialized in the production of type 1 interferons (IFN-I) through TLR7 activation which mediates both immune cell activation and also rea...

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Detalles Bibliográficos
Autores principales:	Abbas, Flora, Cenac, Claire, Youness, Ali, Azar, Pascal, Delobel, Pierre, Guéry, Jean-Charles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441429/ https://www.ncbi.nlm.nih.gov/pubmed/36271499 http://dx.doi.org/10.26508/lsa.202201452

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