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Novel high strength PVA/soy protein isolate composite hydrogels and their properties
High strength polyvinyl alcohol (PVA)/soy protein isolate (SPI) composite hydrogels (EPSG) were constructed by the introduction of PVA into SPI through the crosslinking with epichlorohydrin (ECH) and a freezing-thawing process. The EPSG hydrogels were characterized by scanning electron microscopy, F...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441482/ https://www.ncbi.nlm.nih.gov/pubmed/36072706 http://dx.doi.org/10.3389/fchem.2022.984652 |
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author | Zhao, Yanteng Jin, Lu Liu, Xin Liu, Xue Dong, Shuling Chen, Yun Li, Xianyu Lv, Xianping He, Meng |
author_facet | Zhao, Yanteng Jin, Lu Liu, Xin Liu, Xue Dong, Shuling Chen, Yun Li, Xianyu Lv, Xianping He, Meng |
author_sort | Zhao, Yanteng |
collection | PubMed |
description | High strength polyvinyl alcohol (PVA)/soy protein isolate (SPI) composite hydrogels (EPSG) were constructed by the introduction of PVA into SPI through the crosslinking with epichlorohydrin (ECH) and a freezing-thawing process. The EPSG hydrogels were characterized by scanning electron microscopy, FTIR, X-ray diffraction and compressive test. The results revealed that chemical crosslinking interactions occurred for SPI and PVA during the fabrication process. The composite hydrogels exhibited a homogenous porous structure, indicating certain miscibility between PVA and SPI. The introduction of PVA increased the compressive strength of SPI hydrogels greatly, which could reach as high as 5.38 MPa with the water content ratio of 89.5%. Moreover, the water uptake ratio of completely dried SPI hydrogel (namely xerogel) decreased gradually from 327.4% to 148.1% with the incorporation of PVA, showing a better potential as implants. The cytocompatibility and hemocompatibility of the EPSG hydrogels were evaluated by a series of in vitro experiments. The results showed that the EPSG hydrogels had no cytotoxicity (cell viability values were above 86.7%), good biocompatibility and hemocompatibility, showing potential applications as a direct blood contact material in the field of tissue engineering. |
format | Online Article Text |
id | pubmed-9441482 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-94414822022-09-06 Novel high strength PVA/soy protein isolate composite hydrogels and their properties Zhao, Yanteng Jin, Lu Liu, Xin Liu, Xue Dong, Shuling Chen, Yun Li, Xianyu Lv, Xianping He, Meng Front Chem Chemistry High strength polyvinyl alcohol (PVA)/soy protein isolate (SPI) composite hydrogels (EPSG) were constructed by the introduction of PVA into SPI through the crosslinking with epichlorohydrin (ECH) and a freezing-thawing process. The EPSG hydrogels were characterized by scanning electron microscopy, FTIR, X-ray diffraction and compressive test. The results revealed that chemical crosslinking interactions occurred for SPI and PVA during the fabrication process. The composite hydrogels exhibited a homogenous porous structure, indicating certain miscibility between PVA and SPI. The introduction of PVA increased the compressive strength of SPI hydrogels greatly, which could reach as high as 5.38 MPa with the water content ratio of 89.5%. Moreover, the water uptake ratio of completely dried SPI hydrogel (namely xerogel) decreased gradually from 327.4% to 148.1% with the incorporation of PVA, showing a better potential as implants. The cytocompatibility and hemocompatibility of the EPSG hydrogels were evaluated by a series of in vitro experiments. The results showed that the EPSG hydrogels had no cytotoxicity (cell viability values were above 86.7%), good biocompatibility and hemocompatibility, showing potential applications as a direct blood contact material in the field of tissue engineering. Frontiers Media S.A. 2022-08-22 /pmc/articles/PMC9441482/ /pubmed/36072706 http://dx.doi.org/10.3389/fchem.2022.984652 Text en Copyright © 2022 Zhao, Jin, Liu, Liu, Dong, Chen, Li, Lv and He. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Chemistry Zhao, Yanteng Jin, Lu Liu, Xin Liu, Xue Dong, Shuling Chen, Yun Li, Xianyu Lv, Xianping He, Meng Novel high strength PVA/soy protein isolate composite hydrogels and their properties |
title | Novel high strength PVA/soy protein isolate composite hydrogels and their properties |
title_full | Novel high strength PVA/soy protein isolate composite hydrogels and their properties |
title_fullStr | Novel high strength PVA/soy protein isolate composite hydrogels and their properties |
title_full_unstemmed | Novel high strength PVA/soy protein isolate composite hydrogels and their properties |
title_short | Novel high strength PVA/soy protein isolate composite hydrogels and their properties |
title_sort | novel high strength pva/soy protein isolate composite hydrogels and their properties |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441482/ https://www.ncbi.nlm.nih.gov/pubmed/36072706 http://dx.doi.org/10.3389/fchem.2022.984652 |
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