Cargando…

Novel high strength PVA/soy protein isolate composite hydrogels and their properties

High strength polyvinyl alcohol (PVA)/soy protein isolate (SPI) composite hydrogels (EPSG) were constructed by the introduction of PVA into SPI through the crosslinking with epichlorohydrin (ECH) and a freezing-thawing process. The EPSG hydrogels were characterized by scanning electron microscopy, F...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Yanteng, Jin, Lu, Liu, Xin, Liu, Xue, Dong, Shuling, Chen, Yun, Li, Xianyu, Lv, Xianping, He, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441482/
https://www.ncbi.nlm.nih.gov/pubmed/36072706
http://dx.doi.org/10.3389/fchem.2022.984652
_version_ 1784782584424693760
author Zhao, Yanteng
Jin, Lu
Liu, Xin
Liu, Xue
Dong, Shuling
Chen, Yun
Li, Xianyu
Lv, Xianping
He, Meng
author_facet Zhao, Yanteng
Jin, Lu
Liu, Xin
Liu, Xue
Dong, Shuling
Chen, Yun
Li, Xianyu
Lv, Xianping
He, Meng
author_sort Zhao, Yanteng
collection PubMed
description High strength polyvinyl alcohol (PVA)/soy protein isolate (SPI) composite hydrogels (EPSG) were constructed by the introduction of PVA into SPI through the crosslinking with epichlorohydrin (ECH) and a freezing-thawing process. The EPSG hydrogels were characterized by scanning electron microscopy, FTIR, X-ray diffraction and compressive test. The results revealed that chemical crosslinking interactions occurred for SPI and PVA during the fabrication process. The composite hydrogels exhibited a homogenous porous structure, indicating certain miscibility between PVA and SPI. The introduction of PVA increased the compressive strength of SPI hydrogels greatly, which could reach as high as 5.38 MPa with the water content ratio of 89.5%. Moreover, the water uptake ratio of completely dried SPI hydrogel (namely xerogel) decreased gradually from 327.4% to 148.1% with the incorporation of PVA, showing a better potential as implants. The cytocompatibility and hemocompatibility of the EPSG hydrogels were evaluated by a series of in vitro experiments. The results showed that the EPSG hydrogels had no cytotoxicity (cell viability values were above 86.7%), good biocompatibility and hemocompatibility, showing potential applications as a direct blood contact material in the field of tissue engineering.
format Online
Article
Text
id pubmed-9441482
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-94414822022-09-06 Novel high strength PVA/soy protein isolate composite hydrogels and their properties Zhao, Yanteng Jin, Lu Liu, Xin Liu, Xue Dong, Shuling Chen, Yun Li, Xianyu Lv, Xianping He, Meng Front Chem Chemistry High strength polyvinyl alcohol (PVA)/soy protein isolate (SPI) composite hydrogels (EPSG) were constructed by the introduction of PVA into SPI through the crosslinking with epichlorohydrin (ECH) and a freezing-thawing process. The EPSG hydrogels were characterized by scanning electron microscopy, FTIR, X-ray diffraction and compressive test. The results revealed that chemical crosslinking interactions occurred for SPI and PVA during the fabrication process. The composite hydrogels exhibited a homogenous porous structure, indicating certain miscibility between PVA and SPI. The introduction of PVA increased the compressive strength of SPI hydrogels greatly, which could reach as high as 5.38 MPa with the water content ratio of 89.5%. Moreover, the water uptake ratio of completely dried SPI hydrogel (namely xerogel) decreased gradually from 327.4% to 148.1% with the incorporation of PVA, showing a better potential as implants. The cytocompatibility and hemocompatibility of the EPSG hydrogels were evaluated by a series of in vitro experiments. The results showed that the EPSG hydrogels had no cytotoxicity (cell viability values were above 86.7%), good biocompatibility and hemocompatibility, showing potential applications as a direct blood contact material in the field of tissue engineering. Frontiers Media S.A. 2022-08-22 /pmc/articles/PMC9441482/ /pubmed/36072706 http://dx.doi.org/10.3389/fchem.2022.984652 Text en Copyright © 2022 Zhao, Jin, Liu, Liu, Dong, Chen, Li, Lv and He. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Zhao, Yanteng
Jin, Lu
Liu, Xin
Liu, Xue
Dong, Shuling
Chen, Yun
Li, Xianyu
Lv, Xianping
He, Meng
Novel high strength PVA/soy protein isolate composite hydrogels and their properties
title Novel high strength PVA/soy protein isolate composite hydrogels and their properties
title_full Novel high strength PVA/soy protein isolate composite hydrogels and their properties
title_fullStr Novel high strength PVA/soy protein isolate composite hydrogels and their properties
title_full_unstemmed Novel high strength PVA/soy protein isolate composite hydrogels and their properties
title_short Novel high strength PVA/soy protein isolate composite hydrogels and their properties
title_sort novel high strength pva/soy protein isolate composite hydrogels and their properties
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441482/
https://www.ncbi.nlm.nih.gov/pubmed/36072706
http://dx.doi.org/10.3389/fchem.2022.984652
work_keys_str_mv AT zhaoyanteng novelhighstrengthpvasoyproteinisolatecompositehydrogelsandtheirproperties
AT jinlu novelhighstrengthpvasoyproteinisolatecompositehydrogelsandtheirproperties
AT liuxin novelhighstrengthpvasoyproteinisolatecompositehydrogelsandtheirproperties
AT liuxue novelhighstrengthpvasoyproteinisolatecompositehydrogelsandtheirproperties
AT dongshuling novelhighstrengthpvasoyproteinisolatecompositehydrogelsandtheirproperties
AT chenyun novelhighstrengthpvasoyproteinisolatecompositehydrogelsandtheirproperties
AT lixianyu novelhighstrengthpvasoyproteinisolatecompositehydrogelsandtheirproperties
AT lvxianping novelhighstrengthpvasoyproteinisolatecompositehydrogelsandtheirproperties
AT hemeng novelhighstrengthpvasoyproteinisolatecompositehydrogelsandtheirproperties