Induction of the BRAF(V600E) Mutation in Thyroid Cells Leads to Frequent Hypermethylation

OBJECTIVES. The BRAF(V600E) mutation is a major driver mutation in papillary thyroid cancer. The aim of this study was to elucidate the correlation between DNA methylation and gene expression changes induced by the BRAF(V600E) mutation in thyroid cells. METHODS. We used Nthy/BRAF cell lines generate...

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Detalles Bibliográficos
Autores principales: Yi, Jin Wook, Ha, Seong Yun, Jee, Hyeon-Gun, Kim, Kwangsoo, Kim, Su-jin, Chai, Young Jun, Choi, June Young, Lee, Kyu Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441509/
https://www.ncbi.nlm.nih.gov/pubmed/35538718
http://dx.doi.org/10.21053/ceo.2022.00206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441509/
https://www.ncbi.nlm.nih.gov/pubmed/35538718
http://dx.doi.org/10.21053/ceo.2022.00206

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