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Metabolomics profiling reveals berberine-inhibited inflammatory response in human gingival fibroblasts by regulating the LPS-induced apoptosis signaling pathway

This article examines berberine’s biological effects and molecular mechanisms with an inflammatory response model induced by lipopolysaccharide (LPS) in human gingival fibroblasts (HGFs) using metabolomics. The viability of HGFs was determined using the cell counting kit-8 (CCK8). ELISA was used to...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Guo, Yanyang, Wei, Wenjia, Zhang, Zhongxiao, Xu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441553/
https://www.ncbi.nlm.nih.gov/pubmed/36071855
http://dx.doi.org/10.3389/fphar.2022.940224