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Central carbon metabolism remodeling as a mechanism to develop drug tolerance and drug resistance in Mycobacterium tuberculosis

Suboptimal efficacy of the current antibiotic regimens and frequent emergence of antibiotic-resistant Mycobacterium tuberculosis (Mtb), an etiological agent of tuberculosis (TB), render TB the world’s deadliest infectious disease before the COVID-19 outbreak. Our outdated TB treatment method is desi...

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Detalles Bibliográficos
Autores principales: Eoh, Hyungjin, Liu, Rachel, Lim, Juhyeon, Lee, Jae Jin, Sell, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441700/
https://www.ncbi.nlm.nih.gov/pubmed/36072228
http://dx.doi.org/10.3389/fcimb.2022.958240