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Understanding the contribution of metabolism to Mycobacterium tuberculosis drug tolerance
Treatment of Mycobacterium tuberculosis (Mtb) infections is particularly arduous. One challenge to effectively treating tuberculosis is that drug efficacy in vivo often fails to match drug efficacy in vitro. This is due to multiple reasons, including inadequate drug concentrations reaching Mtb at th...
Autores principales: | Samuels, Amanda N., Wang, Erin R., Harrison, Gregory A., Valenta, Joy C., Stallings, Christina L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441742/ https://www.ncbi.nlm.nih.gov/pubmed/36072222 http://dx.doi.org/10.3389/fcimb.2022.958555 |
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