Stroke risk evaluation for patients with atrial fibrillation: Insights from left atrial appendage

Left atrial appendage (LAA) is believed to be a common site of thrombus formation in patients with atrial fibrillation (AF). However, the commonly-applied stroke risk stratification model (such as. CHA(2)DS(2)-VASc score) does not include any structural or hemodynamic features of LAA. Recent studies...

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Detalles Bibliográficos
Autores principales: Fang, Runxin, Li, Yang, Wang, Jun, Wang, Zidun, Allen, John, Ching, Chi Keong, Zhong, Liang, Li, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441763/
https://www.ncbi.nlm.nih.gov/pubmed/36072865
http://dx.doi.org/10.3389/fcvm.2022.968630
Descripción
Sumario:Left atrial appendage (LAA) is believed to be a common site of thrombus formation in patients with atrial fibrillation (AF). However, the commonly-applied stroke risk stratification model (such as. CHA(2)DS(2)-VASc score) does not include any structural or hemodynamic features of LAA. Recent studies have suggested that it is important to incorporate LAA geometrical and hemodynamic features to evaluate the risk of thrombus formation in LAA, which may better delineate the AF patients for anticoagulant administration and prevent strokes. This review focuses on the LAA-related factors that may be associated with thrombus formation and cardioembolic events.

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