Stroke risk evaluation for patients with atrial fibrillation: Insights from left atrial appendage

Left atrial appendage (LAA) is believed to be a common site of thrombus formation in patients with atrial fibrillation (AF). However, the commonly-applied stroke risk stratification model (such as. CHA(2)DS(2)-VASc score) does not include any structural or hemodynamic features of LAA. Recent studies...

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Autores principales: Fang, Runxin, Li, Yang, Wang, Jun, Wang, Zidun, Allen, John, Ching, Chi Keong, Zhong, Liang, Li, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441763/
https://www.ncbi.nlm.nih.gov/pubmed/36072865
http://dx.doi.org/10.3389/fcvm.2022.968630
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author Fang, Runxin
Li, Yang
Wang, Jun
Wang, Zidun
Allen, John
Ching, Chi Keong
Zhong, Liang
Li, Zhiyong
author_facet Fang, Runxin
Li, Yang
Wang, Jun
Wang, Zidun
Allen, John
Ching, Chi Keong
Zhong, Liang
Li, Zhiyong
author_sort Fang, Runxin
collection PubMed
description Left atrial appendage (LAA) is believed to be a common site of thrombus formation in patients with atrial fibrillation (AF). However, the commonly-applied stroke risk stratification model (such as. CHA(2)DS(2)-VASc score) does not include any structural or hemodynamic features of LAA. Recent studies have suggested that it is important to incorporate LAA geometrical and hemodynamic features to evaluate the risk of thrombus formation in LAA, which may better delineate the AF patients for anticoagulant administration and prevent strokes. This review focuses on the LAA-related factors that may be associated with thrombus formation and cardioembolic events.
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spelling pubmed-94417632022-09-06 Stroke risk evaluation for patients with atrial fibrillation: Insights from left atrial appendage Fang, Runxin Li, Yang Wang, Jun Wang, Zidun Allen, John Ching, Chi Keong Zhong, Liang Li, Zhiyong Front Cardiovasc Med Cardiovascular Medicine Left atrial appendage (LAA) is believed to be a common site of thrombus formation in patients with atrial fibrillation (AF). However, the commonly-applied stroke risk stratification model (such as. CHA(2)DS(2)-VASc score) does not include any structural or hemodynamic features of LAA. Recent studies have suggested that it is important to incorporate LAA geometrical and hemodynamic features to evaluate the risk of thrombus formation in LAA, which may better delineate the AF patients for anticoagulant administration and prevent strokes. This review focuses on the LAA-related factors that may be associated with thrombus formation and cardioembolic events. Frontiers Media S.A. 2022-08-22 /pmc/articles/PMC9441763/ /pubmed/36072865 http://dx.doi.org/10.3389/fcvm.2022.968630 Text en Copyright © 2022 Fang, Li, Wang, Wang, Allen, Ching, Zhong and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Fang, Runxin
Li, Yang
Wang, Jun
Wang, Zidun
Allen, John
Ching, Chi Keong
Zhong, Liang
Li, Zhiyong
Stroke risk evaluation for patients with atrial fibrillation: Insights from left atrial appendage
title Stroke risk evaluation for patients with atrial fibrillation: Insights from left atrial appendage
title_full Stroke risk evaluation for patients with atrial fibrillation: Insights from left atrial appendage
title_fullStr Stroke risk evaluation for patients with atrial fibrillation: Insights from left atrial appendage
title_full_unstemmed Stroke risk evaluation for patients with atrial fibrillation: Insights from left atrial appendage
title_short Stroke risk evaluation for patients with atrial fibrillation: Insights from left atrial appendage
title_sort stroke risk evaluation for patients with atrial fibrillation: insights from left atrial appendage
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441763/
https://www.ncbi.nlm.nih.gov/pubmed/36072865
http://dx.doi.org/10.3389/fcvm.2022.968630
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