Cargando…
Case report: The first description of a Dieulafoy's lesion in the gastric mucosa of a dog
An approximately 12-year-old, 31 kg, male neutered Labrador Retriever was presented to the referring hospital with an acute onset (less than 1 day) of hematemesis and melena. The dog was treated supportively for a presumptive gastric ulcer for 4 days with intravenous fluids, gastro protectants, such...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441867/ https://www.ncbi.nlm.nih.gov/pubmed/36072394 http://dx.doi.org/10.3389/fvets.2022.932435 |
_version_ | 1784782683035926528 |
---|---|
author | Barrantes Murillo, Daniel Felipe Tillson, Michael Koehler, Jennifer W. Sandey, Maninder |
author_facet | Barrantes Murillo, Daniel Felipe Tillson, Michael Koehler, Jennifer W. Sandey, Maninder |
author_sort | Barrantes Murillo, Daniel Felipe |
collection | PubMed |
description | An approximately 12-year-old, 31 kg, male neutered Labrador Retriever was presented to the referring hospital with an acute onset (less than 1 day) of hematemesis and melena. The dog was treated supportively for a presumptive gastric ulcer for 4 days with intravenous fluids, gastro protectants, such as pantoprazole, misoprostol, sucralfate, and barium, as well as an anti-emetic (maropitant) and analgesics (fentanyl, gabapentin, and tramadol). Throughout medical management, the dog continued to require blood transfusions approximately every 24 h. Given the poor medical response, the patient was subjected to an exploratory laparotomy. During surgery, a grossly raised, blister-like lesion on the mucosal surface of the stomach was appreciated on the lesser curvature of the stomach. A partial gastrectomy was performed, and the segment was submitted for histological evaluation. Histologically, there were multiple, tortuous, medium-caliber muscular arteries (>1.0 mm in diameter) in the submucosa. A single large-caliber artery (>0.75 mm in diameter) containing a partially occlusive thrombus extruded through the mucosa and projected on the ulcerated surface. The patient's signs were similar clinically and histopathologically to Dieulafoy's lesion in people. A Dieulafoy's lesion is a potentially life-threatening disorder that causes gastrointestinal (GI) hemorrhage. This lesion is characterized by a dilated, large-caliber, aberrant submucosal artery that erodes through the epithelium and ruptures, resulting in massive and potentially fatal hemorrhage. This lesion has never been documented previously in a dog. |
format | Online Article Text |
id | pubmed-9441867 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-94418672022-09-06 Case report: The first description of a Dieulafoy's lesion in the gastric mucosa of a dog Barrantes Murillo, Daniel Felipe Tillson, Michael Koehler, Jennifer W. Sandey, Maninder Front Vet Sci Veterinary Science An approximately 12-year-old, 31 kg, male neutered Labrador Retriever was presented to the referring hospital with an acute onset (less than 1 day) of hematemesis and melena. The dog was treated supportively for a presumptive gastric ulcer for 4 days with intravenous fluids, gastro protectants, such as pantoprazole, misoprostol, sucralfate, and barium, as well as an anti-emetic (maropitant) and analgesics (fentanyl, gabapentin, and tramadol). Throughout medical management, the dog continued to require blood transfusions approximately every 24 h. Given the poor medical response, the patient was subjected to an exploratory laparotomy. During surgery, a grossly raised, blister-like lesion on the mucosal surface of the stomach was appreciated on the lesser curvature of the stomach. A partial gastrectomy was performed, and the segment was submitted for histological evaluation. Histologically, there were multiple, tortuous, medium-caliber muscular arteries (>1.0 mm in diameter) in the submucosa. A single large-caliber artery (>0.75 mm in diameter) containing a partially occlusive thrombus extruded through the mucosa and projected on the ulcerated surface. The patient's signs were similar clinically and histopathologically to Dieulafoy's lesion in people. A Dieulafoy's lesion is a potentially life-threatening disorder that causes gastrointestinal (GI) hemorrhage. This lesion is characterized by a dilated, large-caliber, aberrant submucosal artery that erodes through the epithelium and ruptures, resulting in massive and potentially fatal hemorrhage. This lesion has never been documented previously in a dog. Frontiers Media S.A. 2022-08-22 /pmc/articles/PMC9441867/ /pubmed/36072394 http://dx.doi.org/10.3389/fvets.2022.932435 Text en Copyright © 2022 Barrantes Murillo, Tillson, Koehler and Sandey. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Veterinary Science Barrantes Murillo, Daniel Felipe Tillson, Michael Koehler, Jennifer W. Sandey, Maninder Case report: The first description of a Dieulafoy's lesion in the gastric mucosa of a dog |
title | Case report: The first description of a Dieulafoy's lesion in the gastric mucosa of a dog |
title_full | Case report: The first description of a Dieulafoy's lesion in the gastric mucosa of a dog |
title_fullStr | Case report: The first description of a Dieulafoy's lesion in the gastric mucosa of a dog |
title_full_unstemmed | Case report: The first description of a Dieulafoy's lesion in the gastric mucosa of a dog |
title_short | Case report: The first description of a Dieulafoy's lesion in the gastric mucosa of a dog |
title_sort | case report: the first description of a dieulafoy's lesion in the gastric mucosa of a dog |
topic | Veterinary Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441867/ https://www.ncbi.nlm.nih.gov/pubmed/36072394 http://dx.doi.org/10.3389/fvets.2022.932435 |
work_keys_str_mv | AT barrantesmurillodanielfelipe casereportthefirstdescriptionofadieulafoyslesioninthegastricmucosaofadog AT tillsonmichael casereportthefirstdescriptionofadieulafoyslesioninthegastricmucosaofadog AT koehlerjenniferw casereportthefirstdescriptionofadieulafoyslesioninthegastricmucosaofadog AT sandeymaninder casereportthefirstdescriptionofadieulafoyslesioninthegastricmucosaofadog |