Squamous cell carcinoma of the hypopharynx in a young woman with Fanconi’s anemia

Fanconi’s anemia is a rare autosomal recessive disorder characterized by congenital malformation, bone marrow failure and genomic instability, with a predisposition to develop malignancies, especially the leukemias and upper aerodigestive tract tumors. Due to inherent characteristics to this syndrom...

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Autores principales: Horta, Henrique de Lins e, Guimarães, Fernando Fernandes, Rocha, Luiz Otávio Savassi, Guimarães, Roberto Eustáquio Santos, Valadares, Eugênia Ribeiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442057/
https://www.ncbi.nlm.nih.gov/pubmed/17308840
http://dx.doi.org/10.1016/S1808-8694(15)31054-5
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author Horta, Henrique de Lins e
Guimarães, Fernando Fernandes
Rocha, Luiz Otávio Savassi
Guimarães, Roberto Eustáquio Santos
Valadares, Eugênia Ribeiro
author_facet Horta, Henrique de Lins e
Guimarães, Fernando Fernandes
Rocha, Luiz Otávio Savassi
Guimarães, Roberto Eustáquio Santos
Valadares, Eugênia Ribeiro
author_sort Horta, Henrique de Lins e
collection PubMed
description Fanconi’s anemia is a rare autosomal recessive disorder characterized by congenital malformation, bone marrow failure and genomic instability, with a predisposition to develop malignancies, especially the leukemias and upper aerodigestive tract tumors. Due to inherent characteristics to this syndrome, the treatment of such neoplasms is particularly difficult. In this paper we report the case of a 24-year-old woman with Fanconi’s anemia who developed a squamous cell carcinoma of the hypopharynx; she had none of the traditional risk factors, such as smoking and alcohol abuse. We also briefly review the literature about this topic
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spelling pubmed-94420572022-09-09 Squamous cell carcinoma of the hypopharynx in a young woman with Fanconi’s anemia Horta, Henrique de Lins e Guimarães, Fernando Fernandes Rocha, Luiz Otávio Savassi Guimarães, Roberto Eustáquio Santos Valadares, Eugênia Ribeiro Braz J Otorhinolaryngol Case Report Fanconi’s anemia is a rare autosomal recessive disorder characterized by congenital malformation, bone marrow failure and genomic instability, with a predisposition to develop malignancies, especially the leukemias and upper aerodigestive tract tumors. Due to inherent characteristics to this syndrome, the treatment of such neoplasms is particularly difficult. In this paper we report the case of a 24-year-old woman with Fanconi’s anemia who developed a squamous cell carcinoma of the hypopharynx; she had none of the traditional risk factors, such as smoking and alcohol abuse. We also briefly review the literature about this topic Elsevier 2015-10-19 /pmc/articles/PMC9442057/ /pubmed/17308840 http://dx.doi.org/10.1016/S1808-8694(15)31054-5 Text en . https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Horta, Henrique de Lins e
Guimarães, Fernando Fernandes
Rocha, Luiz Otávio Savassi
Guimarães, Roberto Eustáquio Santos
Valadares, Eugênia Ribeiro
Squamous cell carcinoma of the hypopharynx in a young woman with Fanconi’s anemia
title Squamous cell carcinoma of the hypopharynx in a young woman with Fanconi’s anemia
title_full Squamous cell carcinoma of the hypopharynx in a young woman with Fanconi’s anemia
title_fullStr Squamous cell carcinoma of the hypopharynx in a young woman with Fanconi’s anemia
title_full_unstemmed Squamous cell carcinoma of the hypopharynx in a young woman with Fanconi’s anemia
title_short Squamous cell carcinoma of the hypopharynx in a young woman with Fanconi’s anemia
title_sort squamous cell carcinoma of the hypopharynx in a young woman with fanconi’s anemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442057/
https://www.ncbi.nlm.nih.gov/pubmed/17308840
http://dx.doi.org/10.1016/S1808-8694(15)31054-5
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