Optogenetic control of YAP cellular localisation and function

YAP, an effector of the Hippo signalling pathway, promotes organ growth and regeneration. Prolonged YAP activation results in uncontrolled proliferation and cancer. Therefore, exogenous regulation of YAP activity has potential translational applications. We present a versatile optogenetic construct...

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Detalles Bibliográficos
Autores principales: Toh, Pearlyn J Y, Lai, Jason K H, Hermann, Anke, Destaing, Olivier, Sheetz, Michael P, Sudol, Marius, Saunders, Timothy E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442306/
https://www.ncbi.nlm.nih.gov/pubmed/35876586
http://dx.doi.org/10.15252/embr.202154401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442306/
https://www.ncbi.nlm.nih.gov/pubmed/35876586
http://dx.doi.org/10.15252/embr.202154401

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