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Global and precise identification of functional miRNA targets in mESCs by integrative analysis

MicroRNA (miRNA) loaded Argonaute (AGO) complexes regulate gene expression via direct base pairing with their mRNA targets. Previous works suggest that up to 60% of mammalian transcripts might be subject to miRNA‐mediated regulation, but it remains largely unknown which fraction of these interaction...

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Detalles Bibliográficos
Autores principales:	Schaefer, Moritz, Nabih, Amena, Spies, Daniel, Hermes, Victoria, Bodak, Maxime, Wischnewski, Harry, Stalder, Patrick, Ngondo, Richard Patryk, Liechti, Luz Angelica, Sajic, Tatjana, Aebersold, Ruedi, Gatfield, David, Ciaudo, Constance
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442311/ https://www.ncbi.nlm.nih.gov/pubmed/35899551 http://dx.doi.org/10.15252/embr.202254762

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