Cargando…
Ahnak depletion accelerates liver regeneration by modulating the TGF-β/Smad signaling pathway
Ahnak, a large protein first identified as an inhibitor of TGF-β signaling in human neuroblastoma, was recently shown to promote TGF-β in some cancers. The TGF-β signaling pathway regulates cell growth, various biological functions, and cancer growth and metastasis. In this study, we used Ahnak knoc...
Autores principales: | Yang, Insook, Son, Yeri, Shin, Jae Hoon, Kim, Il Yong, Seong, Je Kyung |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442348/ https://www.ncbi.nlm.nih.gov/pubmed/35880432 http://dx.doi.org/10.5483/BMBRep.2022.55.8.071 |
Ejemplares similares
-
Ahnak functions as a tumor suppressor via modulation of TGFβ/Smad signaling pathway
por: Lee, I H, et al.
Publicado: (2014) -
AHNAK deficiency promotes browning and lipolysis in mice via increased responsiveness to β-adrenergic signalling
por: Shin, Jae Hoon, et al.
Publicado: (2016) -
AHNAK2 Promotes Migration, Invasion, and Epithelial-Mesenchymal Transition in Lung Adenocarcinoma Cells via the TGF-β/Smad3 Pathway
por: Liu, Gang, et al.
Publicado: (2020) -
Essential role of Ahnak in adipocyte differentiation leading to the transcriptional regulation of Bmpr1α expression
por: Woo, Jong Kyu, et al.
Publicado: (2018) -
Ahnak-knockout mice show susceptibility to Bartonella henselae infection because of CD4+ T cell inactivation and decreased cytokine secretion
por: Choi, Eun Wha, et al.
Publicado: (2019)