The Il6 -39 kb enhancer containing clustered GATA2- and PU.1-binding sites is essential for Il6 expression in murine mast cells

Mast cells serve as a first-line defense of innate immunity. Interleukin-6 (IL-6) induced by bacterial lipopolysaccharide (LPS) in mast cells plays a crucial role in antibacterial protection. The zinc finger transcription factor GATA2 cooperatively functions with the ETS family transcription factor...

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Detalles Bibliográficos
Autores principales: Ohmori, Shin’ya, Takai, Jun, Uemura, Satoshi, Otsuki, Akihito, Mori, Tetsuya, Ohneda, Kinuko, Moriguchi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442365/
https://www.ncbi.nlm.nih.gov/pubmed/36072552
http://dx.doi.org/10.1016/j.isci.2022.104942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442365/
https://www.ncbi.nlm.nih.gov/pubmed/36072552
http://dx.doi.org/10.1016/j.isci.2022.104942

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