Cargando…

Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation

Hypertrophy and recurrent tonsillitis are common indications of tonsillectomy. However, the pathological reports are similar, regardless of clinical aspects. OBJECTIVE: Search for histopathological changes that differentiate palatine tonsils operated because of hypertrophy vis-à-vis those operated b...

Descripción completa

Detalles Bibliográficos
Autores principales: Reis, Luciana Guedes Vilela, de Souza Almeida, Élia Cláudia, da Silva, Juliano Carvalho, de Araújo Pereira, Gilberto, de Fátima Barbosa, Valdirene, Etchebehere, Renata Margarida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442398/
https://www.ncbi.nlm.nih.gov/pubmed/24141676
http://dx.doi.org/10.5935/1808-8694.20130108
Descripción
Sumario:Hypertrophy and recurrent tonsillitis are common indications of tonsillectomy. However, the pathological reports are similar, regardless of clinical aspects. OBJECTIVE: Search for histopathological changes that differentiate palatine tonsils operated because of hypertrophy vis-à-vis those operated because of recurrent tonsillitis. METHOD: A prospective cross-sectional descriptive study involving 46 children divided into group I - 22 with hypertrophy; and group II - 24 with recurrent tonsillitis, in the period between 2010 and 2012, in a public hospital. We evaluated clinical and histopathological features (lymph follicles, germinal centers, fibrosis, necrosis, reticulation, infiltration by plasma cells and neutrophils). RESULTS: The patients' ages ranged between 2 and 11 years (5.17 ± 2.28). In group I, half of the patients had had the latest infection at seven months or more, and all with obstruction degree greater than 3 (≥ 50%). In group II, all had had the latest infection at less than seven months, and most with obstruction degree below 4 (≤ 75%). There was a statistically significant difference in the degree of obstruction (p = 0.0021) and number of germinal centers (p = 0.002) was higher in group I. CONCLUSION: This study suggests that the number of germinal centers is the only histopathological criterion that can be used to differentiate the two groups.