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Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation
Hypertrophy and recurrent tonsillitis are common indications of tonsillectomy. However, the pathological reports are similar, regardless of clinical aspects. OBJECTIVE: Search for histopathological changes that differentiate palatine tonsils operated because of hypertrophy vis-à-vis those operated b...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442398/ https://www.ncbi.nlm.nih.gov/pubmed/24141676 http://dx.doi.org/10.5935/1808-8694.20130108 |
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author | Reis, Luciana Guedes Vilela de Souza Almeida, Élia Cláudia da Silva, Juliano Carvalho de Araújo Pereira, Gilberto de Fátima Barbosa, Valdirene Etchebehere, Renata Margarida |
author_facet | Reis, Luciana Guedes Vilela de Souza Almeida, Élia Cláudia da Silva, Juliano Carvalho de Araújo Pereira, Gilberto de Fátima Barbosa, Valdirene Etchebehere, Renata Margarida |
author_sort | Reis, Luciana Guedes Vilela |
collection | PubMed |
description | Hypertrophy and recurrent tonsillitis are common indications of tonsillectomy. However, the pathological reports are similar, regardless of clinical aspects. OBJECTIVE: Search for histopathological changes that differentiate palatine tonsils operated because of hypertrophy vis-à-vis those operated because of recurrent tonsillitis. METHOD: A prospective cross-sectional descriptive study involving 46 children divided into group I - 22 with hypertrophy; and group II - 24 with recurrent tonsillitis, in the period between 2010 and 2012, in a public hospital. We evaluated clinical and histopathological features (lymph follicles, germinal centers, fibrosis, necrosis, reticulation, infiltration by plasma cells and neutrophils). RESULTS: The patients' ages ranged between 2 and 11 years (5.17 ± 2.28). In group I, half of the patients had had the latest infection at seven months or more, and all with obstruction degree greater than 3 (≥ 50%). In group II, all had had the latest infection at less than seven months, and most with obstruction degree below 4 (≤ 75%). There was a statistically significant difference in the degree of obstruction (p = 0.0021) and number of germinal centers (p = 0.002) was higher in group I. CONCLUSION: This study suggests that the number of germinal centers is the only histopathological criterion that can be used to differentiate the two groups. |
format | Online Article Text |
id | pubmed-9442398 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-94423982022-09-09 Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation Reis, Luciana Guedes Vilela de Souza Almeida, Élia Cláudia da Silva, Juliano Carvalho de Araújo Pereira, Gilberto de Fátima Barbosa, Valdirene Etchebehere, Renata Margarida Braz J Otorhinolaryngol Original Article Hypertrophy and recurrent tonsillitis are common indications of tonsillectomy. However, the pathological reports are similar, regardless of clinical aspects. OBJECTIVE: Search for histopathological changes that differentiate palatine tonsils operated because of hypertrophy vis-à-vis those operated because of recurrent tonsillitis. METHOD: A prospective cross-sectional descriptive study involving 46 children divided into group I - 22 with hypertrophy; and group II - 24 with recurrent tonsillitis, in the period between 2010 and 2012, in a public hospital. We evaluated clinical and histopathological features (lymph follicles, germinal centers, fibrosis, necrosis, reticulation, infiltration by plasma cells and neutrophils). RESULTS: The patients' ages ranged between 2 and 11 years (5.17 ± 2.28). In group I, half of the patients had had the latest infection at seven months or more, and all with obstruction degree greater than 3 (≥ 50%). In group II, all had had the latest infection at less than seven months, and most with obstruction degree below 4 (≤ 75%). There was a statistically significant difference in the degree of obstruction (p = 0.0021) and number of germinal centers (p = 0.002) was higher in group I. CONCLUSION: This study suggests that the number of germinal centers is the only histopathological criterion that can be used to differentiate the two groups. Elsevier 2015-10-08 /pmc/articles/PMC9442398/ /pubmed/24141676 http://dx.doi.org/10.5935/1808-8694.20130108 Text en . https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Original Article Reis, Luciana Guedes Vilela de Souza Almeida, Élia Cláudia da Silva, Juliano Carvalho de Araújo Pereira, Gilberto de Fátima Barbosa, Valdirene Etchebehere, Renata Margarida Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation |
title | Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation |
title_full | Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation |
title_fullStr | Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation |
title_full_unstemmed | Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation |
title_short | Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation |
title_sort | tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442398/ https://www.ncbi.nlm.nih.gov/pubmed/24141676 http://dx.doi.org/10.5935/1808-8694.20130108 |
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