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Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation

Hypertrophy and recurrent tonsillitis are common indications of tonsillectomy. However, the pathological reports are similar, regardless of clinical aspects. OBJECTIVE: Search for histopathological changes that differentiate palatine tonsils operated because of hypertrophy vis-à-vis those operated b...

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Autores principales: Reis, Luciana Guedes Vilela, de Souza Almeida, Élia Cláudia, da Silva, Juliano Carvalho, de Araújo Pereira, Gilberto, de Fátima Barbosa, Valdirene, Etchebehere, Renata Margarida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442398/
https://www.ncbi.nlm.nih.gov/pubmed/24141676
http://dx.doi.org/10.5935/1808-8694.20130108
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author Reis, Luciana Guedes Vilela
de Souza Almeida, Élia Cláudia
da Silva, Juliano Carvalho
de Araújo Pereira, Gilberto
de Fátima Barbosa, Valdirene
Etchebehere, Renata Margarida
author_facet Reis, Luciana Guedes Vilela
de Souza Almeida, Élia Cláudia
da Silva, Juliano Carvalho
de Araújo Pereira, Gilberto
de Fátima Barbosa, Valdirene
Etchebehere, Renata Margarida
author_sort Reis, Luciana Guedes Vilela
collection PubMed
description Hypertrophy and recurrent tonsillitis are common indications of tonsillectomy. However, the pathological reports are similar, regardless of clinical aspects. OBJECTIVE: Search for histopathological changes that differentiate palatine tonsils operated because of hypertrophy vis-à-vis those operated because of recurrent tonsillitis. METHOD: A prospective cross-sectional descriptive study involving 46 children divided into group I - 22 with hypertrophy; and group II - 24 with recurrent tonsillitis, in the period between 2010 and 2012, in a public hospital. We evaluated clinical and histopathological features (lymph follicles, germinal centers, fibrosis, necrosis, reticulation, infiltration by plasma cells and neutrophils). RESULTS: The patients' ages ranged between 2 and 11 years (5.17 ± 2.28). In group I, half of the patients had had the latest infection at seven months or more, and all with obstruction degree greater than 3 (≥ 50%). In group II, all had had the latest infection at less than seven months, and most with obstruction degree below 4 (≤ 75%). There was a statistically significant difference in the degree of obstruction (p = 0.0021) and number of germinal centers (p = 0.002) was higher in group I. CONCLUSION: This study suggests that the number of germinal centers is the only histopathological criterion that can be used to differentiate the two groups.
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spelling pubmed-94423982022-09-09 Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation Reis, Luciana Guedes Vilela de Souza Almeida, Élia Cláudia da Silva, Juliano Carvalho de Araújo Pereira, Gilberto de Fátima Barbosa, Valdirene Etchebehere, Renata Margarida Braz J Otorhinolaryngol Original Article Hypertrophy and recurrent tonsillitis are common indications of tonsillectomy. However, the pathological reports are similar, regardless of clinical aspects. OBJECTIVE: Search for histopathological changes that differentiate palatine tonsils operated because of hypertrophy vis-à-vis those operated because of recurrent tonsillitis. METHOD: A prospective cross-sectional descriptive study involving 46 children divided into group I - 22 with hypertrophy; and group II - 24 with recurrent tonsillitis, in the period between 2010 and 2012, in a public hospital. We evaluated clinical and histopathological features (lymph follicles, germinal centers, fibrosis, necrosis, reticulation, infiltration by plasma cells and neutrophils). RESULTS: The patients' ages ranged between 2 and 11 years (5.17 ± 2.28). In group I, half of the patients had had the latest infection at seven months or more, and all with obstruction degree greater than 3 (≥ 50%). In group II, all had had the latest infection at less than seven months, and most with obstruction degree below 4 (≤ 75%). There was a statistically significant difference in the degree of obstruction (p = 0.0021) and number of germinal centers (p = 0.002) was higher in group I. CONCLUSION: This study suggests that the number of germinal centers is the only histopathological criterion that can be used to differentiate the two groups. Elsevier 2015-10-08 /pmc/articles/PMC9442398/ /pubmed/24141676 http://dx.doi.org/10.5935/1808-8694.20130108 Text en . https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Article
Reis, Luciana Guedes Vilela
de Souza Almeida, Élia Cláudia
da Silva, Juliano Carvalho
de Araújo Pereira, Gilberto
de Fátima Barbosa, Valdirene
Etchebehere, Renata Margarida
Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation
title Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation
title_full Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation
title_fullStr Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation
title_full_unstemmed Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation
title_short Tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation
title_sort tonsillar hyperplasia and recurrent tonsillitis: clinical-histological correlation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442398/
https://www.ncbi.nlm.nih.gov/pubmed/24141676
http://dx.doi.org/10.5935/1808-8694.20130108
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