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Surgical treatment and adjuvant therapies of recurrent respiratory papillomatosis

Recurrent respiratory papillomatosis or recurrent laryngeal papillomatosis is a disease of the larynx caused by human papilloma virus, characterized by verrucous epithelial lesions and usually recurring. In the literature there are several types of treatment, such as surgery to cold, laser and/or us...

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Autores principales: Avelino, Melissa Ameloti Gomes, Zaiden, Tallyta Campos Domingues Teixeira, Gomes, Raquel Oliveira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442437/
https://www.ncbi.nlm.nih.gov/pubmed/24141682
http://dx.doi.org/10.5935/1808-8694.20130114
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author Avelino, Melissa Ameloti Gomes
Zaiden, Tallyta Campos Domingues Teixeira
Gomes, Raquel Oliveira
author_facet Avelino, Melissa Ameloti Gomes
Zaiden, Tallyta Campos Domingues Teixeira
Gomes, Raquel Oliveira
author_sort Avelino, Melissa Ameloti Gomes
collection PubMed
description Recurrent respiratory papillomatosis or recurrent laryngeal papillomatosis is a disease of the larynx caused by human papilloma virus, characterized by verrucous epithelial lesions and usually recurring. In the literature there are several types of treatment, such as surgery to cold, laser and/or use of microdebrider, as of adjuvant therapies; all possible to decrease the permanent sequelae of the disease. OBJECTIVE: To review the literature regarding this disease with emphasis on surgical techniques and adjuvant therapies used today. METHOD: We used the literature review, through surveys based electronic data in the public domain, to search for articles between 1992-2012, using keywords: papilloma, human pappiloma virus infection, larynx, therapeutic, papilloma virus vaccine. RESULTS: We surveyed 357 articles, of which 49 were used as the basis for this review. Scientific studies indicate a reduction of relapse in most adjuvant therapeutic presented. However, the survey showed different methodologies and samples, which did not allow to compare the types of treatment and adjuvant therapies. CONCLUSION: The choice of surgical technique varies among studies, but there is a trend to use the microdebrider. The newer adjuvant therapies, such as cidofovir, quadrivalent vaccine against human papilloma virus and bevacizumab, require further studies.
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spelling pubmed-94424372022-09-09 Surgical treatment and adjuvant therapies of recurrent respiratory papillomatosis Avelino, Melissa Ameloti Gomes Zaiden, Tallyta Campos Domingues Teixeira Gomes, Raquel Oliveira Braz J Otorhinolaryngol Review Article Recurrent respiratory papillomatosis or recurrent laryngeal papillomatosis is a disease of the larynx caused by human papilloma virus, characterized by verrucous epithelial lesions and usually recurring. In the literature there are several types of treatment, such as surgery to cold, laser and/or use of microdebrider, as of adjuvant therapies; all possible to decrease the permanent sequelae of the disease. OBJECTIVE: To review the literature regarding this disease with emphasis on surgical techniques and adjuvant therapies used today. METHOD: We used the literature review, through surveys based electronic data in the public domain, to search for articles between 1992-2012, using keywords: papilloma, human pappiloma virus infection, larynx, therapeutic, papilloma virus vaccine. RESULTS: We surveyed 357 articles, of which 49 were used as the basis for this review. Scientific studies indicate a reduction of relapse in most adjuvant therapeutic presented. However, the survey showed different methodologies and samples, which did not allow to compare the types of treatment and adjuvant therapies. CONCLUSION: The choice of surgical technique varies among studies, but there is a trend to use the microdebrider. The newer adjuvant therapies, such as cidofovir, quadrivalent vaccine against human papilloma virus and bevacizumab, require further studies. Elsevier 2015-10-08 /pmc/articles/PMC9442437/ /pubmed/24141682 http://dx.doi.org/10.5935/1808-8694.20130114 Text en . https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review Article
Avelino, Melissa Ameloti Gomes
Zaiden, Tallyta Campos Domingues Teixeira
Gomes, Raquel Oliveira
Surgical treatment and adjuvant therapies of recurrent respiratory papillomatosis
title Surgical treatment and adjuvant therapies of recurrent respiratory papillomatosis
title_full Surgical treatment and adjuvant therapies of recurrent respiratory papillomatosis
title_fullStr Surgical treatment and adjuvant therapies of recurrent respiratory papillomatosis
title_full_unstemmed Surgical treatment and adjuvant therapies of recurrent respiratory papillomatosis
title_short Surgical treatment and adjuvant therapies of recurrent respiratory papillomatosis
title_sort surgical treatment and adjuvant therapies of recurrent respiratory papillomatosis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442437/
https://www.ncbi.nlm.nih.gov/pubmed/24141682
http://dx.doi.org/10.5935/1808-8694.20130114
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