Cargando…

Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo()()

INTRODUCTION: Changes in carbohydrate metabolism may lead to recurrence of benign paroxysmal positional vertigo. OBJECTIVE: To evaluate the influence of the disturbance of carbohydrate metabolism in the recurrence of idiopathic BPPV. METHODS: A longitudinal prospective study of a cohort, with 41 mon...

Descripción completa

Detalles Bibliográficos
Autores principales: Webster, Guilherme, Sens, Patrícia Maria, Salmito, Márcio Cavalcante, Cavalcante, José Diogo Rijo, dos Santos, Paula Regina Bonifácio, da Silva, Ana Lívia Muniz, de Souza, Érica Carla Figueiredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442681/
https://www.ncbi.nlm.nih.gov/pubmed/26122875
http://dx.doi.org/10.1016/j.bjorl.2014.09.008
_version_ 1784782871839375360
author Webster, Guilherme
Sens, Patrícia Maria
Salmito, Márcio Cavalcante
Cavalcante, José Diogo Rijo
dos Santos, Paula Regina Bonifácio
da Silva, Ana Lívia Muniz
de Souza, Érica Carla Figueiredo
author_facet Webster, Guilherme
Sens, Patrícia Maria
Salmito, Márcio Cavalcante
Cavalcante, José Diogo Rijo
dos Santos, Paula Regina Bonifácio
da Silva, Ana Lívia Muniz
de Souza, Érica Carla Figueiredo
author_sort Webster, Guilherme
collection PubMed
description INTRODUCTION: Changes in carbohydrate metabolism may lead to recurrence of benign paroxysmal positional vertigo. OBJECTIVE: To evaluate the influence of the disturbance of carbohydrate metabolism in the recurrence of idiopathic BPPV. METHODS: A longitudinal prospective study of a cohort, with 41 months follow-up. We analyzed the results of 72 glucose–insulin curves in patients with recurrence of BPPV. The curves were classified into intolerance, hyperinsulinemia, hyperglycemia and normal. RESULTS: The RR for hyperinsulinism was 4.66 and p = 0.0015. Existing hyperglycemia showed an RR = 2.47, with p = 0.0123. Glucose intolerance had a RR of 0.63, with p = 0.096. When the examination was within normal limits, the result was RR = 0.2225 and p = 0.030. DISCUSSION: Metabolic changes can cause dizziness and vertigo and are very common in people who have cochleovestibular disorders. However, few studies discuss the relationship between idiopathic BPPV and alterations in carbohydrate metabolism. In the present study, we found that both hyperglycemia and hyperinsulinemia are risk factors for the recurrence of BPPV, whereas a normal test was considered a protective factor; all these were statistically significant. Glucose intolerance that was already present was not statistically significant in the group evaluated. CONCLUSION: Hyperinsulinemia and hyperglycemia are risk factors for the recurrence of idiopathic BPPV and a normal exam is considered a protective factor.
format Online
Article
Text
id pubmed-9442681
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-94426812022-09-09 Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo()() Webster, Guilherme Sens, Patrícia Maria Salmito, Márcio Cavalcante Cavalcante, José Diogo Rijo dos Santos, Paula Regina Bonifácio da Silva, Ana Lívia Muniz de Souza, Érica Carla Figueiredo Braz J Otorhinolaryngol Original Article INTRODUCTION: Changes in carbohydrate metabolism may lead to recurrence of benign paroxysmal positional vertigo. OBJECTIVE: To evaluate the influence of the disturbance of carbohydrate metabolism in the recurrence of idiopathic BPPV. METHODS: A longitudinal prospective study of a cohort, with 41 months follow-up. We analyzed the results of 72 glucose–insulin curves in patients with recurrence of BPPV. The curves were classified into intolerance, hyperinsulinemia, hyperglycemia and normal. RESULTS: The RR for hyperinsulinism was 4.66 and p = 0.0015. Existing hyperglycemia showed an RR = 2.47, with p = 0.0123. Glucose intolerance had a RR of 0.63, with p = 0.096. When the examination was within normal limits, the result was RR = 0.2225 and p = 0.030. DISCUSSION: Metabolic changes can cause dizziness and vertigo and are very common in people who have cochleovestibular disorders. However, few studies discuss the relationship between idiopathic BPPV and alterations in carbohydrate metabolism. In the present study, we found that both hyperglycemia and hyperinsulinemia are risk factors for the recurrence of BPPV, whereas a normal test was considered a protective factor; all these were statistically significant. Glucose intolerance that was already present was not statistically significant in the group evaluated. CONCLUSION: Hyperinsulinemia and hyperglycemia are risk factors for the recurrence of idiopathic BPPV and a normal exam is considered a protective factor. Elsevier 2015-06-09 /pmc/articles/PMC9442681/ /pubmed/26122875 http://dx.doi.org/10.1016/j.bjorl.2014.09.008 Text en © 2015 Associac¸ão Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Webster, Guilherme
Sens, Patrícia Maria
Salmito, Márcio Cavalcante
Cavalcante, José Diogo Rijo
dos Santos, Paula Regina Bonifácio
da Silva, Ana Lívia Muniz
de Souza, Érica Carla Figueiredo
Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo()()
title Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo()()
title_full Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo()()
title_fullStr Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo()()
title_full_unstemmed Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo()()
title_short Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo()()
title_sort hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo()()
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442681/
https://www.ncbi.nlm.nih.gov/pubmed/26122875
http://dx.doi.org/10.1016/j.bjorl.2014.09.008
work_keys_str_mv AT websterguilherme hyperinsulinemiaandhyperglycemiariskfactorsforrecurrenceofbenignparoxysmalpositionalvertigo
AT senspatriciamaria hyperinsulinemiaandhyperglycemiariskfactorsforrecurrenceofbenignparoxysmalpositionalvertigo
AT salmitomarciocavalcante hyperinsulinemiaandhyperglycemiariskfactorsforrecurrenceofbenignparoxysmalpositionalvertigo
AT cavalcantejosediogorijo hyperinsulinemiaandhyperglycemiariskfactorsforrecurrenceofbenignparoxysmalpositionalvertigo
AT dossantospaulareginabonifacio hyperinsulinemiaandhyperglycemiariskfactorsforrecurrenceofbenignparoxysmalpositionalvertigo
AT dasilvaanaliviamuniz hyperinsulinemiaandhyperglycemiariskfactorsforrecurrenceofbenignparoxysmalpositionalvertigo
AT desouzaericacarlafigueiredo hyperinsulinemiaandhyperglycemiariskfactorsforrecurrenceofbenignparoxysmalpositionalvertigo