ADSCs stimulated by VEGF-C alleviate intestinal inflammation via dual mechanisms of enhancing lymphatic drainage by a VEGF-C/VEGFR-3-dependent mechanism and inhibiting the NF-κB pathway by the secretome

BACKGROUND: Adipose-derived stem cells (ADSCs) have provided promising applications for Crohn’s disease (CD). However, the practical efficacy of ADSCs remains controversial, and their mechanism is still unclear. Based on the pathogenesis of dysregulated immune responses and abnormal lymphatic altera...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Ye, Chen, Li, Peng, Li, Chuanding, Shu, Weigang, Zhao, Yujie, Wang, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442958/
https://www.ncbi.nlm.nih.gov/pubmed/36064450
http://dx.doi.org/10.1186/s13287-022-03132-3

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