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Clinical and polysomnographic predictors of laryngopharyngeal reflux in obstructive sleep apnea syndrome()
INTRODUCTION: Obstructive sleep apnea syndrome and laryngopharyngeal reflux are diseases with a high prevalence in the overall population; however, it remains unclear whether they are diseases with the same risk factors present in the same populations or if there is any association between them. OBJ...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443018/ https://www.ncbi.nlm.nih.gov/pubmed/29730042 http://dx.doi.org/10.1016/j.bjorl.2018.03.007 |
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author | Caparroz, Fábio Azevedo Campanholo, Milena de Almeida Torres Regina, Caroline Gomez Park, Sung Woo Haddad, Leonardo Gregório, Luís Carlos Haddad, Fernanda Louise Martinho |
author_facet | Caparroz, Fábio Azevedo Campanholo, Milena de Almeida Torres Regina, Caroline Gomez Park, Sung Woo Haddad, Leonardo Gregório, Luís Carlos Haddad, Fernanda Louise Martinho |
author_sort | Caparroz, Fábio Azevedo |
collection | PubMed |
description | INTRODUCTION: Obstructive sleep apnea syndrome and laryngopharyngeal reflux are diseases with a high prevalence in the overall population; however, it remains unclear whether they are diseases with the same risk factors present in the same populations or if there is any association between them. OBJECTIVES: To evaluate and determine the prevalence of laryngopharyngeal reflux in patients with moderate and severe obstructive apnea syndrome and also to determine its predictive factors. METHODS: Historical cohort, cross-sectional study of patients aged 18–70 years, referred to a tertiary service Otorhinolaryngology outpatient clinic with a polysomnographic diagnosis of moderate or severe obstructive sleep apnea syndrome. The reflux symptom index questionnaire and the reflux finding score at indirect videolaryngoscopy were applied to the assessed population, considering the inclusion and exclusion criteria. RESULTS: Fifty-six patients were evaluated, of which 64.3% had a positive laryngopharyngeal reflux (positive reflux symptom index and/or positive endolaryngeal reflux finding score). Body mass index was a predictor of reflux presence in this group of patients with moderate to severe obstructive sleep apnea syndrome. In patients with positive score for endoscopic findings and reflux symptom index (12.3%), there was a trend toward significance for a higher mean apnea–hypopnea index and a higher percentage of sleep time with oxyhemoglobin saturation below 90% (p = 0.05). CONCLUSION: The prevalence of laryngopharyngeal reflux was higher in this group of patients with moderate to severe obstructive sleep apnea syndrome, and the body mass index was a predictor of laryngopharyngeal reflux in these patients. There was a trend toward greater oxyhemoglobin desaturation in patients with a positive score for reflux symptoms index (RSI) and reflux finding score (RFS). |
format | Online Article Text |
id | pubmed-9443018 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-94430182022-09-09 Clinical and polysomnographic predictors of laryngopharyngeal reflux in obstructive sleep apnea syndrome() Caparroz, Fábio Azevedo Campanholo, Milena de Almeida Torres Regina, Caroline Gomez Park, Sung Woo Haddad, Leonardo Gregório, Luís Carlos Haddad, Fernanda Louise Martinho Braz J Otorhinolaryngol Original Article INTRODUCTION: Obstructive sleep apnea syndrome and laryngopharyngeal reflux are diseases with a high prevalence in the overall population; however, it remains unclear whether they are diseases with the same risk factors present in the same populations or if there is any association between them. OBJECTIVES: To evaluate and determine the prevalence of laryngopharyngeal reflux in patients with moderate and severe obstructive apnea syndrome and also to determine its predictive factors. METHODS: Historical cohort, cross-sectional study of patients aged 18–70 years, referred to a tertiary service Otorhinolaryngology outpatient clinic with a polysomnographic diagnosis of moderate or severe obstructive sleep apnea syndrome. The reflux symptom index questionnaire and the reflux finding score at indirect videolaryngoscopy were applied to the assessed population, considering the inclusion and exclusion criteria. RESULTS: Fifty-six patients were evaluated, of which 64.3% had a positive laryngopharyngeal reflux (positive reflux symptom index and/or positive endolaryngeal reflux finding score). Body mass index was a predictor of reflux presence in this group of patients with moderate to severe obstructive sleep apnea syndrome. In patients with positive score for endoscopic findings and reflux symptom index (12.3%), there was a trend toward significance for a higher mean apnea–hypopnea index and a higher percentage of sleep time with oxyhemoglobin saturation below 90% (p = 0.05). CONCLUSION: The prevalence of laryngopharyngeal reflux was higher in this group of patients with moderate to severe obstructive sleep apnea syndrome, and the body mass index was a predictor of laryngopharyngeal reflux in these patients. There was a trend toward greater oxyhemoglobin desaturation in patients with a positive score for reflux symptoms index (RSI) and reflux finding score (RFS). Elsevier 2018-04-14 /pmc/articles/PMC9443018/ /pubmed/29730042 http://dx.doi.org/10.1016/j.bjorl.2018.03.007 Text en © 2018 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Original Article Caparroz, Fábio Azevedo Campanholo, Milena de Almeida Torres Regina, Caroline Gomez Park, Sung Woo Haddad, Leonardo Gregório, Luís Carlos Haddad, Fernanda Louise Martinho Clinical and polysomnographic predictors of laryngopharyngeal reflux in obstructive sleep apnea syndrome() |
title | Clinical and polysomnographic predictors of laryngopharyngeal reflux in obstructive sleep apnea syndrome() |
title_full | Clinical and polysomnographic predictors of laryngopharyngeal reflux in obstructive sleep apnea syndrome() |
title_fullStr | Clinical and polysomnographic predictors of laryngopharyngeal reflux in obstructive sleep apnea syndrome() |
title_full_unstemmed | Clinical and polysomnographic predictors of laryngopharyngeal reflux in obstructive sleep apnea syndrome() |
title_short | Clinical and polysomnographic predictors of laryngopharyngeal reflux in obstructive sleep apnea syndrome() |
title_sort | clinical and polysomnographic predictors of laryngopharyngeal reflux in obstructive sleep apnea syndrome() |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443018/ https://www.ncbi.nlm.nih.gov/pubmed/29730042 http://dx.doi.org/10.1016/j.bjorl.2018.03.007 |
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