The E3 Ligase TRIM4 Facilitates SET Ubiquitin‐Mediated Degradation to Enhance ER‐α Action in Breast Cancer

Estrogen receptor alpha (ER‐α) action is critical for hormone‐dependent breast cancer, and ER‐α dysregulation can lead to the emergence of resistance to endocrine therapy. Here, it is found that TRIM4 is downregulated in tamoxifen (TAM)‐resistant breast cancer cells, while the loss of TRIM4 is assoc...

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Detalles Bibliográficos
Autores principales: Han, Dianwen, Wang, Lijuan, Long, Li, Su, Peng, Luo, Dan, Zhang, Hanwen, Li, Zheng, Chen, Bing, Zhao, Wenjing, Zhang, Ning, Wang, Xiaolong, Liang, Yiran, Li, Yaming, Hu, Guohong, Yang, Qifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443474/
https://www.ncbi.nlm.nih.gov/pubmed/35843886
http://dx.doi.org/10.1002/advs.202201701

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