Cargando…
Clinicopathological study of patients with head and neck sarcomas
Sarcomas are rare tumors, mainly stemming from the embryonic mesoderm, with a high grade of morbidity and mortality. OBJECTIVE: To carry out a retrospective study of head and neck sarcoma cases between 1999 and 2008 in three specialized centers in the city of Fortaleza. MATERIALS AND METHODS: Data c...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443710/ https://www.ncbi.nlm.nih.gov/pubmed/21739016 http://dx.doi.org/10.1590/S1808-86942011000300019 |
_version_ | 1784783047173865472 |
---|---|
author | Pacheco, Isabela Alves Alves, Ana Paula Negreiros Nunes Mota, Mário Rogério Lima de Almeida, Paulo César Holanda, Marcelo Esmeraldo de Souza, Eric Fernandes Sousa, Fabricio Bitu |
author_facet | Pacheco, Isabela Alves Alves, Ana Paula Negreiros Nunes Mota, Mário Rogério Lima de Almeida, Paulo César Holanda, Marcelo Esmeraldo de Souza, Eric Fernandes Sousa, Fabricio Bitu |
author_sort | Pacheco, Isabela Alves |
collection | PubMed |
description | Sarcomas are rare tumors, mainly stemming from the embryonic mesoderm, with a high grade of morbidity and mortality. OBJECTIVE: To carry out a retrospective study of head and neck sarcoma cases between 1999 and 2008 in three specialized centers in the city of Fortaleza. MATERIALS AND METHODS: Data collection was based on the charts of the patients in the study. For statistical analysis purposes we used the chi-square associations and the z test for proportions. RESULTS: We found records of 36 patients, and the most affected ones were adult brown males, in the age range between 20 and 59 years - mean age of 39.7. The man/woman ratio was 1.76:1. The most prevalent histological type was the rhabdomyosarcoma and their most common locations were the face and the neck. Most of the sample was made up of live patients without evidence of the disease in the last visit - 41.6% of the cases. The most common treatment modes were the combination of surgery + radiotherapy + chemotherapy and surgery + radiotherapy, with 27.8% of the cases each. CONCLUSION: Sarcomas have a great histological variability and may have numerous locations. Since these are rare and not well-known lesions, new epidemiological studies must be carried out in order to enhance our understanding of the disease. |
format | Online Article Text |
id | pubmed-9443710 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-94437102022-09-09 Clinicopathological study of patients with head and neck sarcomas Pacheco, Isabela Alves Alves, Ana Paula Negreiros Nunes Mota, Mário Rogério Lima de Almeida, Paulo César Holanda, Marcelo Esmeraldo de Souza, Eric Fernandes Sousa, Fabricio Bitu Braz J Otorhinolaryngol Original Article Sarcomas are rare tumors, mainly stemming from the embryonic mesoderm, with a high grade of morbidity and mortality. OBJECTIVE: To carry out a retrospective study of head and neck sarcoma cases between 1999 and 2008 in three specialized centers in the city of Fortaleza. MATERIALS AND METHODS: Data collection was based on the charts of the patients in the study. For statistical analysis purposes we used the chi-square associations and the z test for proportions. RESULTS: We found records of 36 patients, and the most affected ones were adult brown males, in the age range between 20 and 59 years - mean age of 39.7. The man/woman ratio was 1.76:1. The most prevalent histological type was the rhabdomyosarcoma and their most common locations were the face and the neck. Most of the sample was made up of live patients without evidence of the disease in the last visit - 41.6% of the cases. The most common treatment modes were the combination of surgery + radiotherapy + chemotherapy and surgery + radiotherapy, with 27.8% of the cases each. CONCLUSION: Sarcomas have a great histological variability and may have numerous locations. Since these are rare and not well-known lesions, new epidemiological studies must be carried out in order to enhance our understanding of the disease. Elsevier 2015-10-19 /pmc/articles/PMC9443710/ /pubmed/21739016 http://dx.doi.org/10.1590/S1808-86942011000300019 Text en . https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Original Article Pacheco, Isabela Alves Alves, Ana Paula Negreiros Nunes Mota, Mário Rogério Lima de Almeida, Paulo César Holanda, Marcelo Esmeraldo de Souza, Eric Fernandes Sousa, Fabricio Bitu Clinicopathological study of patients with head and neck sarcomas |
title | Clinicopathological study of patients with head and neck sarcomas |
title_full | Clinicopathological study of patients with head and neck sarcomas |
title_fullStr | Clinicopathological study of patients with head and neck sarcomas |
title_full_unstemmed | Clinicopathological study of patients with head and neck sarcomas |
title_short | Clinicopathological study of patients with head and neck sarcomas |
title_sort | clinicopathological study of patients with head and neck sarcomas |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443710/ https://www.ncbi.nlm.nih.gov/pubmed/21739016 http://dx.doi.org/10.1590/S1808-86942011000300019 |
work_keys_str_mv | AT pachecoisabelaalves clinicopathologicalstudyofpatientswithheadandnecksarcomas AT alvesanapaulanegreirosnunes clinicopathologicalstudyofpatientswithheadandnecksarcomas AT motamariorogeriolima clinicopathologicalstudyofpatientswithheadandnecksarcomas AT dealmeidapaulocesar clinicopathologicalstudyofpatientswithheadandnecksarcomas AT holandamarceloesmeraldo clinicopathologicalstudyofpatientswithheadandnecksarcomas AT desouzaericfernandes clinicopathologicalstudyofpatientswithheadandnecksarcomas AT sousafabriciobitu clinicopathologicalstudyofpatientswithheadandnecksarcomas |