Cargando…

Clinicopathological study of patients with head and neck sarcomas

Sarcomas are rare tumors, mainly stemming from the embryonic mesoderm, with a high grade of morbidity and mortality. OBJECTIVE: To carry out a retrospective study of head and neck sarcoma cases between 1999 and 2008 in three specialized centers in the city of Fortaleza. MATERIALS AND METHODS: Data c...

Descripción completa

Detalles Bibliográficos
Autores principales: Pacheco, Isabela Alves, Alves, Ana Paula Negreiros Nunes, Mota, Mário Rogério Lima, de Almeida, Paulo César, Holanda, Marcelo Esmeraldo, de Souza, Eric Fernandes, Sousa, Fabricio Bitu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443710/
https://www.ncbi.nlm.nih.gov/pubmed/21739016
http://dx.doi.org/10.1590/S1808-86942011000300019
_version_ 1784783047173865472
author Pacheco, Isabela Alves
Alves, Ana Paula Negreiros Nunes
Mota, Mário Rogério Lima
de Almeida, Paulo César
Holanda, Marcelo Esmeraldo
de Souza, Eric Fernandes
Sousa, Fabricio Bitu
author_facet Pacheco, Isabela Alves
Alves, Ana Paula Negreiros Nunes
Mota, Mário Rogério Lima
de Almeida, Paulo César
Holanda, Marcelo Esmeraldo
de Souza, Eric Fernandes
Sousa, Fabricio Bitu
author_sort Pacheco, Isabela Alves
collection PubMed
description Sarcomas are rare tumors, mainly stemming from the embryonic mesoderm, with a high grade of morbidity and mortality. OBJECTIVE: To carry out a retrospective study of head and neck sarcoma cases between 1999 and 2008 in three specialized centers in the city of Fortaleza. MATERIALS AND METHODS: Data collection was based on the charts of the patients in the study. For statistical analysis purposes we used the chi-square associations and the z test for proportions. RESULTS: We found records of 36 patients, and the most affected ones were adult brown males, in the age range between 20 and 59 years - mean age of 39.7. The man/woman ratio was 1.76:1. The most prevalent histological type was the rhabdomyosarcoma and their most common locations were the face and the neck. Most of the sample was made up of live patients without evidence of the disease in the last visit - 41.6% of the cases. The most common treatment modes were the combination of surgery + radiotherapy + chemotherapy and surgery + radiotherapy, with 27.8% of the cases each. CONCLUSION: Sarcomas have a great histological variability and may have numerous locations. Since these are rare and not well-known lesions, new epidemiological studies must be carried out in order to enhance our understanding of the disease.
format Online
Article
Text
id pubmed-9443710
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-94437102022-09-09 Clinicopathological study of patients with head and neck sarcomas Pacheco, Isabela Alves Alves, Ana Paula Negreiros Nunes Mota, Mário Rogério Lima de Almeida, Paulo César Holanda, Marcelo Esmeraldo de Souza, Eric Fernandes Sousa, Fabricio Bitu Braz J Otorhinolaryngol Original Article Sarcomas are rare tumors, mainly stemming from the embryonic mesoderm, with a high grade of morbidity and mortality. OBJECTIVE: To carry out a retrospective study of head and neck sarcoma cases between 1999 and 2008 in three specialized centers in the city of Fortaleza. MATERIALS AND METHODS: Data collection was based on the charts of the patients in the study. For statistical analysis purposes we used the chi-square associations and the z test for proportions. RESULTS: We found records of 36 patients, and the most affected ones were adult brown males, in the age range between 20 and 59 years - mean age of 39.7. The man/woman ratio was 1.76:1. The most prevalent histological type was the rhabdomyosarcoma and their most common locations were the face and the neck. Most of the sample was made up of live patients without evidence of the disease in the last visit - 41.6% of the cases. The most common treatment modes were the combination of surgery + radiotherapy + chemotherapy and surgery + radiotherapy, with 27.8% of the cases each. CONCLUSION: Sarcomas have a great histological variability and may have numerous locations. Since these are rare and not well-known lesions, new epidemiological studies must be carried out in order to enhance our understanding of the disease. Elsevier 2015-10-19 /pmc/articles/PMC9443710/ /pubmed/21739016 http://dx.doi.org/10.1590/S1808-86942011000300019 Text en . https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Article
Pacheco, Isabela Alves
Alves, Ana Paula Negreiros Nunes
Mota, Mário Rogério Lima
de Almeida, Paulo César
Holanda, Marcelo Esmeraldo
de Souza, Eric Fernandes
Sousa, Fabricio Bitu
Clinicopathological study of patients with head and neck sarcomas
title Clinicopathological study of patients with head and neck sarcomas
title_full Clinicopathological study of patients with head and neck sarcomas
title_fullStr Clinicopathological study of patients with head and neck sarcomas
title_full_unstemmed Clinicopathological study of patients with head and neck sarcomas
title_short Clinicopathological study of patients with head and neck sarcomas
title_sort clinicopathological study of patients with head and neck sarcomas
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443710/
https://www.ncbi.nlm.nih.gov/pubmed/21739016
http://dx.doi.org/10.1590/S1808-86942011000300019
work_keys_str_mv AT pachecoisabelaalves clinicopathologicalstudyofpatientswithheadandnecksarcomas
AT alvesanapaulanegreirosnunes clinicopathologicalstudyofpatientswithheadandnecksarcomas
AT motamariorogeriolima clinicopathologicalstudyofpatientswithheadandnecksarcomas
AT dealmeidapaulocesar clinicopathologicalstudyofpatientswithheadandnecksarcomas
AT holandamarceloesmeraldo clinicopathologicalstudyofpatientswithheadandnecksarcomas
AT desouzaericfernandes clinicopathologicalstudyofpatientswithheadandnecksarcomas
AT sousafabriciobitu clinicopathologicalstudyofpatientswithheadandnecksarcomas