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Use of inhaled versus oral steroids for acute dysphonia
Acute dysphonia is a frequent condition in clinical practice. Its treatment, especially in adults, is not well established in the literature. Steroids are the most recommended drug treatment. However, the existing studies are not enough to establish superiority among the different steroids and the b...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443858/ https://www.ncbi.nlm.nih.gov/pubmed/23670326 http://dx.doi.org/10.5935/1808-8694.20130035 |
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author | de Souza, Andréa Moreira Veiga de Campos Duprat, André Costa, Rejane Cardoso de Oliveira Pimenta, Janaína de Sá Andrade, Fernanda Fonseca da Silva, Fernanda Ferreira |
author_facet | de Souza, Andréa Moreira Veiga de Campos Duprat, André Costa, Rejane Cardoso de Oliveira Pimenta, Janaína de Sá Andrade, Fernanda Fonseca da Silva, Fernanda Ferreira |
author_sort | de Souza, Andréa Moreira Veiga |
collection | PubMed |
description | Acute dysphonia is a frequent condition in clinical practice. Its treatment, especially in adults, is not well established in the literature. Steroids are the most recommended drug treatment. However, the existing studies are not enough to establish superiority among the different steroids and the best route of administration. OBJECTIVE: This prospective clinical study aimed at comparing the effect of inhaling steroids as a dry powder with the effect of oral steroids to treat acute dysphonia. METHOD: We assessed 32 adult patients, broken down into two groups of 16 patients in each one of the treatments, before and seven days after the use of the medication. The patients were submitted to videolaryngoscopy and perceptive and acoustic voice assessment. RESULT: Oral and inhalation treatment significantly reduced hyperemia and edema, and improved the muco-ondulatory movement; nonetheless, edema reduction was statistically more significant (p = 0.012) in the patients treated with the inhalation form of the drug. However, comparing the values of the auditory perceptive analysis and the acoustic measures after treatment between the groups was not statistically significant. CONCLUSION: There was a significant improvement in the acute laryngitis concerning the assessments carried out in all the patients assessed, concerning the two treatments. The inhalation steroid treatment was significantly more effective in reducing the edema. |
format | Online Article Text |
id | pubmed-9443858 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-94438582022-09-09 Use of inhaled versus oral steroids for acute dysphonia de Souza, Andréa Moreira Veiga de Campos Duprat, André Costa, Rejane Cardoso de Oliveira Pimenta, Janaína de Sá Andrade, Fernanda Fonseca da Silva, Fernanda Ferreira Braz J Otorhinolaryngol Original Article Acute dysphonia is a frequent condition in clinical practice. Its treatment, especially in adults, is not well established in the literature. Steroids are the most recommended drug treatment. However, the existing studies are not enough to establish superiority among the different steroids and the best route of administration. OBJECTIVE: This prospective clinical study aimed at comparing the effect of inhaling steroids as a dry powder with the effect of oral steroids to treat acute dysphonia. METHOD: We assessed 32 adult patients, broken down into two groups of 16 patients in each one of the treatments, before and seven days after the use of the medication. The patients were submitted to videolaryngoscopy and perceptive and acoustic voice assessment. RESULT: Oral and inhalation treatment significantly reduced hyperemia and edema, and improved the muco-ondulatory movement; nonetheless, edema reduction was statistically more significant (p = 0.012) in the patients treated with the inhalation form of the drug. However, comparing the values of the auditory perceptive analysis and the acoustic measures after treatment between the groups was not statistically significant. CONCLUSION: There was a significant improvement in the acute laryngitis concerning the assessments carried out in all the patients assessed, concerning the two treatments. The inhalation steroid treatment was significantly more effective in reducing the edema. Elsevier 2015-11-02 /pmc/articles/PMC9443858/ /pubmed/23670326 http://dx.doi.org/10.5935/1808-8694.20130035 Text en . https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Original Article de Souza, Andréa Moreira Veiga de Campos Duprat, André Costa, Rejane Cardoso de Oliveira Pimenta, Janaína de Sá Andrade, Fernanda Fonseca da Silva, Fernanda Ferreira Use of inhaled versus oral steroids for acute dysphonia |
title | Use of inhaled versus oral steroids for acute dysphonia |
title_full | Use of inhaled versus oral steroids for acute dysphonia |
title_fullStr | Use of inhaled versus oral steroids for acute dysphonia |
title_full_unstemmed | Use of inhaled versus oral steroids for acute dysphonia |
title_short | Use of inhaled versus oral steroids for acute dysphonia |
title_sort | use of inhaled versus oral steroids for acute dysphonia |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443858/ https://www.ncbi.nlm.nih.gov/pubmed/23670326 http://dx.doi.org/10.5935/1808-8694.20130035 |
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