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Use of inhaled versus oral steroids for acute dysphonia

Acute dysphonia is a frequent condition in clinical practice. Its treatment, especially in adults, is not well established in the literature. Steroids are the most recommended drug treatment. However, the existing studies are not enough to establish superiority among the different steroids and the b...

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Autores principales: de Souza, Andréa Moreira Veiga, de Campos Duprat, André, Costa, Rejane Cardoso, de Oliveira Pimenta, Janaína, de Sá Andrade, Fernanda Fonseca, da Silva, Fernanda Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443858/
https://www.ncbi.nlm.nih.gov/pubmed/23670326
http://dx.doi.org/10.5935/1808-8694.20130035
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author de Souza, Andréa Moreira Veiga
de Campos Duprat, André
Costa, Rejane Cardoso
de Oliveira Pimenta, Janaína
de Sá Andrade, Fernanda Fonseca
da Silva, Fernanda Ferreira
author_facet de Souza, Andréa Moreira Veiga
de Campos Duprat, André
Costa, Rejane Cardoso
de Oliveira Pimenta, Janaína
de Sá Andrade, Fernanda Fonseca
da Silva, Fernanda Ferreira
author_sort de Souza, Andréa Moreira Veiga
collection PubMed
description Acute dysphonia is a frequent condition in clinical practice. Its treatment, especially in adults, is not well established in the literature. Steroids are the most recommended drug treatment. However, the existing studies are not enough to establish superiority among the different steroids and the best route of administration. OBJECTIVE: This prospective clinical study aimed at comparing the effect of inhaling steroids as a dry powder with the effect of oral steroids to treat acute dysphonia. METHOD: We assessed 32 adult patients, broken down into two groups of 16 patients in each one of the treatments, before and seven days after the use of the medication. The patients were submitted to videolaryngoscopy and perceptive and acoustic voice assessment. RESULT: Oral and inhalation treatment significantly reduced hyperemia and edema, and improved the muco-ondulatory movement; nonetheless, edema reduction was statistically more significant (p = 0.012) in the patients treated with the inhalation form of the drug. However, comparing the values of the auditory perceptive analysis and the acoustic measures after treatment between the groups was not statistically significant. CONCLUSION: There was a significant improvement in the acute laryngitis concerning the assessments carried out in all the patients assessed, concerning the two treatments. The inhalation steroid treatment was significantly more effective in reducing the edema.
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spelling pubmed-94438582022-09-09 Use of inhaled versus oral steroids for acute dysphonia de Souza, Andréa Moreira Veiga de Campos Duprat, André Costa, Rejane Cardoso de Oliveira Pimenta, Janaína de Sá Andrade, Fernanda Fonseca da Silva, Fernanda Ferreira Braz J Otorhinolaryngol Original Article Acute dysphonia is a frequent condition in clinical practice. Its treatment, especially in adults, is not well established in the literature. Steroids are the most recommended drug treatment. However, the existing studies are not enough to establish superiority among the different steroids and the best route of administration. OBJECTIVE: This prospective clinical study aimed at comparing the effect of inhaling steroids as a dry powder with the effect of oral steroids to treat acute dysphonia. METHOD: We assessed 32 adult patients, broken down into two groups of 16 patients in each one of the treatments, before and seven days after the use of the medication. The patients were submitted to videolaryngoscopy and perceptive and acoustic voice assessment. RESULT: Oral and inhalation treatment significantly reduced hyperemia and edema, and improved the muco-ondulatory movement; nonetheless, edema reduction was statistically more significant (p = 0.012) in the patients treated with the inhalation form of the drug. However, comparing the values of the auditory perceptive analysis and the acoustic measures after treatment between the groups was not statistically significant. CONCLUSION: There was a significant improvement in the acute laryngitis concerning the assessments carried out in all the patients assessed, concerning the two treatments. The inhalation steroid treatment was significantly more effective in reducing the edema. Elsevier 2015-11-02 /pmc/articles/PMC9443858/ /pubmed/23670326 http://dx.doi.org/10.5935/1808-8694.20130035 Text en . https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Article
de Souza, Andréa Moreira Veiga
de Campos Duprat, André
Costa, Rejane Cardoso
de Oliveira Pimenta, Janaína
de Sá Andrade, Fernanda Fonseca
da Silva, Fernanda Ferreira
Use of inhaled versus oral steroids for acute dysphonia
title Use of inhaled versus oral steroids for acute dysphonia
title_full Use of inhaled versus oral steroids for acute dysphonia
title_fullStr Use of inhaled versus oral steroids for acute dysphonia
title_full_unstemmed Use of inhaled versus oral steroids for acute dysphonia
title_short Use of inhaled versus oral steroids for acute dysphonia
title_sort use of inhaled versus oral steroids for acute dysphonia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443858/
https://www.ncbi.nlm.nih.gov/pubmed/23670326
http://dx.doi.org/10.5935/1808-8694.20130035
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