Repeat controlled human malaria infection of healthy UK adults with blood-stage Plasmodium falciparum: Safety and parasite growth dynamics

In endemic settings it is known that natural malaria immunity is gradually acquired following repeated exposures. Here we sought to assess whether similar acquisition of blood-stage malaria immunity would occur following repeated parasite exposure by controlled human malaria infection (CHMI). We rep...

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Detalles Bibliográficos
Autores principales: Salkeld, Jo, Themistocleous, Yrene, Barrett, Jordan R., Mitton, Celia H., Rawlinson, Thomas A., Payne, Ruth O., Hou, Mimi M., Khozoee, Baktash, Edwards, Nick J., Nielsen, Carolyn M., Sandoval, Diana Muñoz, Bach, Florian A., Nahrendorf, Wiebke, Ramon, Raquel Lopez, Baker, Megan, Ramos-Lopez, Fernando, Folegatti, Pedro M., Quinkert, Doris, Ellis, Katherine J., Poulton, Ian D., Lawrie, Alison M., Cho, Jee-Sun, Nugent, Fay L., Spence, Philip J., Silk, Sarah E., Draper, Simon J., Minassian, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444061/
https://www.ncbi.nlm.nih.gov/pubmed/36072606
http://dx.doi.org/10.3389/fimmu.2022.984323

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