Hydrolysis improves the inhibition efficacy of bovine lactoferrin against infection by SARS-CoV-2 pseudovirus

The entry of SARS-CoV-2 into host cells may involve the spike protein cleavage by cathepsin L (CTSL). Certain food proteins such as lactoferrin (Lf) inhibit CTSL. The current study investigated the impact of hydrolysis (0–180 min) by proteinase K on electrophoretic pattern, secondary structure, cath...

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Detalles Bibliográficos
Autores principales: Patil, Devashree, Chen, Siyu, Fogliano, Vincenzo, Madadlou, Ashkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444154/
https://www.ncbi.nlm.nih.gov/pubmed/36089931
http://dx.doi.org/10.1016/j.idairyj.2022.105488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444154/
https://www.ncbi.nlm.nih.gov/pubmed/36089931
http://dx.doi.org/10.1016/j.idairyj.2022.105488

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