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Preclinical Profile of Gadoquatrane: A Novel Tetrameric, Macrocyclic High Relaxivity Gadolinium-Based Contrast Agent

The aim of this report was to characterize the key physicochemical, pharmacokinetic (PK), and magnetic resonance imaging (MRI) properties of gadoquatrane (BAY 1747846), a newly designed tetrameric, macrocyclic, extracellular gadolinium-based contrast agent (GBCA) with high relaxivity and stability....

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Detalles Bibliográficos
Autores principales: Lohrke, Jessica, Berger, Markus, Frenzel, Thomas, Hilger, Christoph-Stephan, Jost, Gregor, Panknin, Olaf, Bauser, Marcus, Ebert, Wolfgang, Pietsch, Hubertus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444293/
https://www.ncbi.nlm.nih.gov/pubmed/35703267
http://dx.doi.org/10.1097/RLI.0000000000000889