Macrophages and neutrophils are necessary for ER stress-induced β cell loss

Persistent endoplasmic reticulum (ER) stress induces islet inflammation and β cell loss. How islet inflammation contributes to β cell loss remains uncertain. We have reported previously that chronic overnutrition-induced ER stress in β cells causes Ripk3-mediated islet inflammation, macrophage recru...

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Detalles Bibliográficos
Autores principales: Yang, Bingyuan, Yang, Liu, Wang, Yueyang, Maddison, Lisette A., Tang, Zihan, Haigh, Sander, Gong, Yulong, Zhang, Yue, Covington, Brittney A., Bosma, Karin J., Tong, Xin, Page-McCaw, Patrick, Gannon, Maureen, Deng, Qing, Chen, Wenbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444341/
https://www.ncbi.nlm.nih.gov/pubmed/36001973
http://dx.doi.org/10.1016/j.celrep.2022.111255

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