Cargando…

Multi-omic, Single-Cell, and Biochemical Profiles of Astronauts Guide Pharmacological Strategies for Returning to Gravity

The National Aeronautics and Space Administration (NASA) Twins Study created an integrative molecular profile of an astronaut during NASA’s first 1-year mission on the International Space Station (ISS) and included comparisons to an identical Earth-bound twin. The unique biochemical profiles observe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gertz, Monica L., Chin, Christopher R., Tomoiaga, Delia, MacKay, Matthew, Chang, Christina, Butler, Daniel, Afshinnekoo, Ebrahim, Bezdan, Daniela, Schmidt, Michael A., Mozsary, Christopher, Melnick, Ari, Garrett-Bakelman, Francine, Crucian, Brian, Lee, Stuart M.C., Zwart, Sara R., Smith, Scott M., Meydan, Cem, Mason, Christopher E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444344/ https://www.ncbi.nlm.nih.gov/pubmed/33242408 http://dx.doi.org/10.1016/j.celrep.2020.108429

Ejemplares similares

Clonal Hematopoiesis Before, During, and After Human Spaceflight
por: Mencia-Trinchant, Nuria, et al.
Publicado: (2020)

Long-term spaceflight and the cardiovascular system
por: Vernice, Nicholas A, et al.
Publicado: (2020)

Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers
por: Bezdan, Daniela, et al.
Publicado: (2020)

The Impact of Heterogeneity on Single-Cell Sequencing
por: Goldman, Samantha L., et al.
Publicado: (2019)

Time-resolved molecular measurements reveal changes in astronauts during spaceflight
por: Zheng, Minzhang, et al.
Publicado: (2023)

methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles
por: Akalin, Altuna, et al.
Publicado: (2012)

Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development
por: Malkani, Sherina, et al.
Publicado: (2020)

Latent virus reactivation in astronauts on the international space station
por: Mehta, Satish K., et al.
Publicado: (2017)

Herpes Virus Reactivation in Astronauts During Spaceflight and Its Application on Earth
por: Rooney, Bridgette V., et al.
Publicado: (2019)

The Microbe Directory: An annotated, searchable inventory of microbes’ characteristics
por: Shaaban, Heba, et al.
Publicado: (2018)

Predicting chromosome damage in astronauts participating in international space station missions
por: Feiveson, Alan, et al.
Publicado: (2021)

Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution
por: Garrett-Bakelman, Francine E., et al.
Publicado: (2015)

SARS-CoV-2 Pandemic Impacts on NASA Ground Operations to Protect ISS Astronauts
por: Makedonas, George, et al.
Publicado: (2020)

Improved gastrointestinal health for irritable bowel syndrome with metagenome-guided interventions
por: Meydan, Cem, et al.
Publicado: (2020)

Neutrophil-to-Lymphocyte Ratio: A Biomarker to Monitor the Immune Status of Astronauts
por: Paul, Amber M., et al.
Publicado: (2020)

The influence of spaceflight on the astronaut salivary microbiome and the search for a microbiome biomarker for viral reactivation
por: Urbaniak, Camilla, et al.
Publicado: (2020)

Increased core body temperature in astronauts during long-duration space missions
por: Stahn, Alexander C., et al.
Publicado: (2017)

Astronauts For Hire: The Emergence of a Commercial Astronaut Corps
por: Seedhouse, Erik
Publicado: (2012)

Tele-echocardiography – Made for astronauts, now in hospitals
por: Balasingam, M., et al.
Publicado: (2017)

AMS WITH ASTRONAUTS
por: Vanden Broeck, Renilde
Publicado: (2019)

Physicians as Astronauts
por: Thirsk, Robert
Publicado: (2011)

Handbook of astronautics
por: Odintsov, V A, et al.
Publicado: (1968)

Principles of astronautics
por: Vertregt, M
Publicado: (1960)

Reply to “Risk of severe COVID-19 infection in International Space Station astronauts despite routine pre-mission measures”
por: Crucian, Brian E., et al.
Publicado: (2021)

An optimized algorithm for detecting and annotating regional differential methylation
por: Li, Sheng, et al.
Publicado: (2013)

Space Omics and Tissue Response in Astronaut Skeletal Muscle after Short and Long Duration Missions
por: Blottner, Dieter, et al.
Publicado: (2023)

NASA's scientist-astronauts
por: David, Shayler, et al.
Publicado: (2007)

Astronautics: summary and prospects
por: Kiselev, Anatoly Ivanovich, et al.
Publicado: (2003)

Space Film: The Astronaut
Publicado: (1991)

American astronaut at CERN
por: CERN Press Office. Geneva
Publicado: (1969)

Study of the impact of long-duration space missions at the International Space Station on the astronaut microbiome
por: Voorhies, Alexander A., et al.
Publicado: (2019)

Next generation of astronauts or ESA astronaut 2.0 concept and spotlight on immunity
por: Jacob, Pauline, et al.
Publicado: (2023)

Space Flight Calcium: Implications for Astronaut Health, Spacecraft Operations, and Earth
por: Smith, Scott M., et al.
Publicado: (2012)

Host transcriptional responses in nasal swabs identify potential SARS-CoV-2 infection in PCR negative patients
por: Saravia-Butler, Amanda M., et al.
Publicado: (2022)

Improved feasibility of astronaut short-radius artificial gravity through a 50-day incremental, personalized, vestibular acclimation protocol
por: Bretl, Kathrine N., et al.
Publicado: (2020)

XIIIth International Astronautical Congress
por: Hersey, N Boneff I, et al.
Publicado: (1964)

Interplanetary flight: an introduction to astronautics
por: Clarke, Arthur C
Publicado: (1960)

Space radiation and astronaut safety
por: Seedhouse, Erik
Publicado: (2018)

Applicability of the actigraphy for astronauts in spaceflight
por: Kawada, Tomoyuki
Publicado: (2016)

Hibernating astronauts—science or fiction?
por: Choukèr, A., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_7lvmhtfeiv7c29gav1e8lm6474