Cargando…

FKN/NR Signaling Pathway Regulates Hippocampal Inflammatory Responses: the Survival of Hippocampal Neurons in Diabetic Rats with Chronic Unpredictable Mild Stress

AIM: To investigate the mechanism via which FKN/CX3CR1 signaling abnormalities mediate N-methyl-D-aspartic acid receptor (NMDA) overexcitation-induced hippocampal neuronal injury in diabetic rats complicated with depression (DD). METHODS: Sixty rats were randomly divided into 5 groups. The depressio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Zhuo, Zhao, Hongqing, Liu, Jian, Han, Yuanshan, Wang, Yuhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444384/ https://www.ncbi.nlm.nih.gov/pubmed/36072409 http://dx.doi.org/10.1155/2022/8980627

Ejemplares similares

Glu-mGluR2/3-ERK Signaling Regulates Apoptosis of Hippocampal Neurons in Diabetic-Depression Model Rats
por: Liu, Zhuo, et al.
Publicado: (2019)

Dynamic effects of chronic unpredictable mild stress on the hippocampal transcriptome in rats
por: Li, Feng, et al.
Publicado: (2022)

Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis
por: Meng, Pan, et al.
Publicado: (2023)

Chronic clomipramine treatment increases hippocampal volume in rats exposed to chronic unpredictable mild stress
por: Zhang, Shanshan, et al.
Publicado: (2022)

Unpredictable Chronic Mild Stress Suppresses the Incorporation of New Neurons at the Caudal Pole of the Chicken Hippocampal Formation
por: Gualtieri, F., et al.
Publicado: (2019)

The Impacts of Swimming Exercise on Hippocampal Expression of Neurotrophic Factors in Rats Exposed to Chronic Unpredictable Mild Stress
por: Jiang, Pei, et al.
Publicado: (2014)

β-Asarone Reverses Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior and Promotes Hippocampal Neurogenesis in Rats
por: Dong, Haiying, et al.
Publicado: (2014)

Chronic Unpredictable Mild Stress Aggravates Mood Disorder, Cognitive Impairment, and Brain Insulin Resistance in Diabetic Rat
por: Yang, Hui, et al.
Publicado: (2018)

Nobiletin Ameliorates the Deficits in Hippocampal BDNF, TrkB, and Synapsin I Induced by Chronic Unpredictable Mild Stress
por: Li, Jing, et al.
Publicado: (2013)

Resatorvid Relieves Breast Cancer Complicated with Depression by Inactivating Hippocampal Microglia Through TLR4/NF-κB/NLRP3 Signaling Pathway
por: Luo, Weixu, et al.
Publicado: (2020)

Role of hippocampal p11 in the sustained antidepressant effect of ketamine in the chronic unpredictable mild stress model
por: Sun, H-L, et al.
Publicado: (2016)

Contribution of hippocampal BDNF/CREB signaling pathway and gut microbiota to emotional behavior impairment induced by chronic unpredictable mild stress during pregnancy in rats offspring
por: Zhao, Feng, et al.
Publicado: (2022)

Dynamic changes of behaviors, dentate gyrus neurogenesis and hippocampal miR-124 expression in rats with depression induced by chronic unpredictable mild stress
por: Huang, Yun-Ling, et al.
Publicado: (2019)

Apocynum Leaf Extract Suppresses the Progress of Atherosclerosis in Rats via the FKN/SYK/p38 Signal Pathway
por: Zhang, Dan, et al.
Publicado: (2021)

Xiaoyao Kangai Jieyu Fang, a Chinese Herbal Formulation, Ameliorates Cancer-Related Depression Concurrent with Breast Cancer in Mice via Promoting Hippocampal Synaptic Plasticity
por: Meng, Pan, et al.
Publicado: (2018)

Epigallocatechin-3-Gallate Attenuates Impairment of Learning and Memory in Chronic Unpredictable Mild Stress-Treated Rats by Restoring Hippocampal Autophagic Flux
por: Gu, Hong-Feng, et al.
Publicado: (2014)

Luteolin Induced Hippocampal Neuronal Pyroptosis Inhibition by Regulation of miR-124-3p/TNF-α/TRAF6 Axis in Mice Affected by Breast-Cancer-Related Depression
por: Zhu, Qing, et al.
Publicado: (2022)

Correction: Epigallocatechin-3-Gallate Attenuates Impairment of Learning and Memory in Chronic Unpredictable Mild Stress-Treated Rats by Restoring Hippocampal Autophagic Flux
Publicado: (2015)

Apocynum venetum Leaf Extract Exerts Antidepressant-Like Effects and Inhibits Hippocampal and Cortical Apoptosis of Rats Exposed to Chronic Unpredictable Mild Stress
por: Wu, Ting, et al.
Publicado: (2018)

Damage of hippocampal neurons in rats with chronic alcoholism
por: Du, Ailin, et al.
Publicado: (2014)

Amentoflavone protects hippocampal neurons: anti-inflammatory, antioxidative, and antiapoptotic effects
por: Zhang, Zhen, et al.
Publicado: (2015)

Delay-dependent impairment of spatial working memory with inhibition of NR2B-containing NMDA receptors in hippocampal CA1 region of rats
por: Zhang, Xue-Han, et al.
Publicado: (2013)

Icariin Protects Hippocampal Neurons From Endoplasmic Reticulum Stress and NF-κB Mediated Apoptosis in Fetal Rat Hippocampal Neurons and Asthma Rats
por: Liu, Jiaqi, et al.
Publicado: (2020)

Beneficial effects of running exercise on hippocampal microglia and neuroinflammation in chronic unpredictable stress-induced depression model rats
por: Xiao, Kai, et al.
Publicado: (2021)

Chronic Zinc Exposure Decreases the Surface Expression of NR2A-Containing NMDA Receptors in Cultured Hippocampal Neurons
por: Zhu, Jia, et al.
Publicado: (2012)

Irisin stimulates protective signaling pathways in rat hippocampal neurons
por: Lourenco, Mychael V., et al.
Publicado: (2022)

Electro-Acupuncture Alleviates Chronic Unpredictable Stress-Induced Depressive- and Anxiety-Like Behavior and Hippocampal Neuroinflammation in Rat Model of Depression
por: Yue, Na, et al.
Publicado: (2018)

Chronic Hippocampal Abnormalities and Blunted HPA Axis in an Animal Model of Repeated Unpredictable Stress
por: Algamal, Moustafa, et al.
Publicado: (2018)

Blockade of NR2A-Containing NMDA Receptors Induces Tau Phosphorylation in Rat Hippocampal Slices
por: Allyson, Julie, et al.
Publicado: (2010)

Odor Enrichment Increases Hippocampal Neuron Numbers in Mouse
por: Rusznák, Zoltán, et al.
Publicado: (2018)

Chronic Unpredictable Mild Stress in Rats Induces Colonic Inflammation
por: Wei, Lina, et al.
Publicado: (2019)

Xiaoyao powder alleviates the hippocampal neuron damage in chronic unpredictable mild stress-induced depression model rats in hippocampus via connexin 43Cx43/glucocorticoid receptor/brain-derived neurotrophic factor signaling pathway
por: Zhang, Yuanyuan, et al.
Publicado: (2022)

Toxic effect of acrylamide on the development of hippocampal neurons of weaning rats
por: Lai, Sheng-min, et al.
Publicado: (2017)

Cucurbitacin B Exerts Significant Antidepressant-Like Effects in a Chronic Unpredictable Mild Stress Model of Depression: Involvement of the Hippocampal BDNF-TrkB System
por: Ge, Jian-Bin, et al.
Publicado: (2023)

Cytotoxicity of gamma-ray in rat immature hippocampal neurons
por: Yang, Miyoung, et al.
Publicado: (2011)

Susceptibility of rat hippocampal neurons to hypothermia during development
por: Seo, Kyung Ah, et al.
Publicado: (2013)

Vitamin D3 reduces hippocampal NR2A and anxiety in nicotine withdrawal mice
por: Wu, Bingxue, et al.
Publicado: (2021)

Hydrogen Sulfide Inhibits Chronic Unpredictable Mild Stress-Induced Depressive-Like Behavior by Upregulation of Sirt-1: Involvement in Suppression of Hippocampal Endoplasmic Reticulum Stress
por: Liu, Shu-Yun, et al.
Publicado: (2017)

Electroacupuncture Stimulation Suppresses Postoperative Inflammatory Response and Hippocampal Neuronal Injury
por: Wang, Xiang-feng, et al.
Publicado: (2022)

Xiaoyaosan Alleviates Hippocampal Glutamate-Induced Toxicity in the CUMS Rats via NR2B and PI3K/Akt Signaling Pathway
por: Zhou, Xue-Ming, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_tppnn31d6fajbp44poq1pg7lft